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Optimized Single-Slab Three-dimensional Spin-Echo MR Imaging of the Brain¹

¹ From the Dept of Radiology, Box 800170, University of Virginia School of Medicine, Charlottesville, VA 22908 (J.P.M., J.R.B.); Dept of Nuclear Engineering, Massachusetts Institute of Technology, Cambridge (S.B.); and Depts of Radiology, Children’s Hospital (R.V.M., R.L.R.) and Brigham and Women’s Hospital (R.V.M., C.R.G.G., F.A.J.), Harvard Medical School, Boston, Mass. Received Jan 4, 1999; revision requested Mar 17; final revision received Nov 26; accepted Dec 17. J.P.M., S.B., R.V.M., C.R.G.G., F.A.J., and J.R.B. supported in part by grant NS-35142 from the National Institute of Neurological Disorders and Stroke. Address correspondence to J.P.M. (e-mail: jpm7r@virginia.edu).

The development and optimization of spin-echo–based, single-slab, three-dimensional techniques for magnetic resonance imaging of the whole brain are described. T1-weighted and T2-weighted image sets with a volume resolution of 1 mm³ and fluid-attenuated inversion-recovery image sets with a volume resolution of 3 mm³ were obtained in acquisition times of less than 10 minutes per image set.

Index terms: Brain, abnormalities, 10.121411, 10.363, 10.3637, 10.871 • Brain, MR, 10.121411, 10.121413, 10.121416 • Magnetic resonance (MR), pulse sequences, 10.121411, 10.121413, 10.121416 • Magnetic resonance (MR), rapid imaging, 10.121411, 10.121413, 10.121416 • Magnetic resonance (MR), three-dimensional, 10.121411, 10.121413, 10.121416

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