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Breast Imaging |
1 From the Departments of Radiology (D.T.S., D.M.I.), Medical Oncology (A.R.H., R.W.C.), Pathology (T.I.G., K.W.N.), and Radiation Oncology (S.L.B., D.G.), Stanford University Hospital, 300 Pasteur Dr, Stanford, CA 94305. Received September 24, 1999; revision requested December 15; revision received February 17, 2000; accepted March 7. Address correspondence to D.M.I.
A 33-year-old woman with a strong family history of breast cancer who was referred for mammography 5 weeks after completing lactation was found to have new diffuse bilateral microcalcifications in the breast ducts. Contrast materialenhanced magnetic resonance imaging of the breast showed bilateral patchy areas of abnormal enhancement. Large-core needle biopsy showed diffuse calcifications within expanded benign ducts in a background of lactational change, without evidence of malignancy. To the authors knowledge, these calcifications have not been previously reported and are possibly related to milk stasis or apoptosis associated with lactation.
Index terms: Breast, biopsy, 00.1261 Breast, calcification, 00.54, 00.811 Breast, lactation, 00.8119 Breast, MR, 00.121411, 00.121417, 00.12143 Breast, US, 00.12981 Breast radiography, 00.11, 00.113
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