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(Radiology. 2001;218:267-273.)
© RSNA, 2001


Technical Developments

Chest CT: Automated Nodule Detection and Assessment of Change over Time—Preliminary Experience1

Jane P. Ko, MD and Margrit Betke, PhD

1 From the Department of Radiology, Massachusetts General Hospital, Boston (J.P.K.); and the Computer Science Department, Boston University, Boston, Mass (M.B.). Received January 20, 2000; revision requested March 3; revision received April 25; accepted May 1. Address correspondence to J.P.K., Department of Radiology, New York University Medical Center, 560 First Ave, New York, NY 10016 (e-mail: jane.ko@med.nyu.edu).

The authors developed a computer system that automatically identifies nodules at chest computed tomography, quantifies their diameter, and assesses for change in size at follow-up. The automated nodule detection system identified 318 (86%) of 370 nodules in 16 studies (eight initial and eight follow-up studies) obtained in eight oncology patients with known nodules. Assessment of change in nodule size by the computer matched that by the thoracic radiologist (Spearman rank correlation coefficient, 0.932).

Index terms: Computed tomography (CT), computer programs • Computed tomography (CT), image processing • Computers, diagnostic aid • Lung, nodule, 60.281




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