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(Radiology. 2001;219:258-263.)
© RSNA, 2001

Technical Developments

First-Pass Myocardial Perfusion MR Imaging with Interleaved Notched Saturation: Feasibility Study1

Glenn S. Slavin, PhD, Steven D. Wolff, MD, PhD, Sandeep N. Gupta, PhD and Thomas K. F. Foo, PhD

1 From GE Medical Systems, Milwaukee, Wis (G.S.S., S.N.G., T.K.F.F.); and the Cardiovascular Research Foundation and the Lenox Hill Heart and Vascular Institute, New York, NY (S.D.W.). Received April 3, 2000; revision requested June 5; revision received June 30; accepted July 11. Address correspondence to G.S.S., GE Medical Systems, Johns Hopkins Hospital, 600 N Wolfe St, Rm 110 MRI, Baltimore, MD 21287 (e-mail: glenn.slavin@med.ge.com).

The authors evaluated a magnetization preparation scheme with a "notched" section profile for T1-weighted first-pass myocardial perfusion magnetic resonance (MR) imaging at 1.5 T. The pulse sequence consisted of a preparation sequence followed by an interleaved gradient-echo echo-planar sequence. Image contrast was evaluated in a feasibility study in 12 adult patients. The notched saturation pulse allowed long magnetization recovery times without sacrificing section coverage. Image contrast between normal and ischemic myocardium was excellent.

Index terms: Heart, perfusion, 511.12144 • Magnetic resonance (MR), contrast enhancement, 511.12143 • Myocardium, blood supply, 511.76, 511.771 • Myocardium, MR, 511.121412, 511.12143




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