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(Radiology. 2001;219:823-827.)
© RSNA, 2001

Technical Developments

Echo-enhanced Transcranial Color-coded US: Clinical Usefulness of Intravenous Infusion versus Bolus Injection of SH U 508A1

Thilo Hölscher, MD, Felix Schlachetzki, MD, Albrecht Bauer, MD, Ludger Rosin, MD, Birgit Götz, MS and Ulrich Bogdahn, MD

1 From the Department of Neurology, University of Regensburg, Universitätsstrasse 84, D-93053 Regensburg, Germany (T.H., F.S., L.R., B.G., U.B.); and the Department of Clinical Development Diagnostics, Schering, Berlin, Germany (A.B.). Received January 25, 2000; revision requested March 30; final revision received October 31; accepted December 12. Address correspondence to T.H. (e-mail: thilo.hoelscher@klinik.uni-regensburg.de).

Twelve patients with insufficient transcranial Doppler signal underwent transcranial color-coded ultrasonography before and after administration of SH U 508A with different modes of administration. Clinically useful enhancement time after bolus injection was surpassed by that after standard infusion (1 mL/min), whereas further prolongation was observed after individualized infusion. Intravenous infusion of SH U 508A provides a prolonged useful enhancement compared with that after bolus injection.

Index terms: Arteries, US, 13.12988 • Brain neoplasms, US, 10.30, 10.12988 • Microbubbles, 13.12988 • Ultrasound (US), contrast media, 13.12988 • Ultrasound (US), Doppler studies, 13.12988




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[Abstract] [Full Text] [PDF]


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