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Technical Developments |
1 From the Departments of Radiology, Brigham and Women’s Hospital (S.E.M., H.M., Y.M., F.A.J.) and Children’s Hospital (R.V.M.), Harvard Medical School, 75 Francis St, Boston, MA 02115; and the Diagnostics Center, Pannon University of Agriculture, Kaposvar, Hungary (P.B., G.B., I.R.). Received June 27, 2000; revision requested August 7; revision received September 6; accepted September 11. S.E.M. supported by grants from the Whitaker Foundation and the National Institutes of Health (NIH 1R01 NS39335-01A1). P.B. supported by Hungarian Scientific Research Fund (OTKA grants F 016343, T 034200). Address correspondence to S.E.M. (e-mail: stephan@bwh.harvard.edu).
Magnetic resonance line scan diffusion imaging of the brain, with diffusion weighting between 5 and 5,000 sec/mm2, was performed in healthy subjects and patients with a 1.5-T machine. For each voxel, biexponential signal decay fits produced two apparent diffusion constants and respective signal amplitudes. Images based on these parameters show potential for use in the differentiation of gray and white matter, edema, and tumor.
Index terms: Brain, edema, 10.86 • Brain, gray matter • Brain, white matter • Brain neoplasms, MR, 10.121411, 10.12143 • Magnetic resonance (MR), contrast enhancement, 10.12143 • Magnetic resonance (MR), diffusion study, 10.12144 • Magnetic resonance (MR), tissue characterization
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