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(Radiology. 2001;220:441-447.)
© RSNA, 2001


Cardiac Imaging

MR Flow Measurement in the Internal Mammary Artery–to–Coronary Artery Bypass Graft: Comparison with Graft Stenosis at Radiographic Angiography1

Nanaka Ishida, MD, Hajime Sakuma, MD, Bayard P. Cruz, MD, Takatsugu Shimono, MD, Toshiya Tokui, MD, Isao Yada, MD, Kan Takeda, MD and Charles B. Higgins, MD

1 From the Departments of Radiology (N.I., H.S., K.T.) and Thoracic Surgery (B.P.C., T.S., T.T., I.Y.), Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan; and the Department of Radiology, University of California Medical Center, San Francisco (C.B.H.). Received July 20, 2000; revision requested September 7; final revision received February 15, 2001; accepted February 26. Address correspondence to N.I. (e-mail: nanaka@clin.medic.mie-u.ac.jp).

PURPOSE: To evaluate the sensitivity and specificity of breath-hold magnetic resonance (MR) flow measurement for detection of significant stenosis in internal mammary artery bypass grafts.

MATERIALS AND METHODS: Twenty-six consecutive patients who had undergone coronary artery bypass surgery were examined. Breath-hold velocity-encoded cine MR images were obtained at the midpoint of the internal mammary artery between its origin from the subclavian artery and the distal anastomosis to the left anterior descending artery.

RESULTS: MR images were obtained successfully in 24 patients. At conventional angiography, no significant stenosis was observed in 17 patients (group A), and significant stenosis (diameter > 70%) was observed in seven patients (group B). The mean diastolic-to-systolic peak velocity ratio in group B (0.61 ± 0.44 [SD]) was significantly lower than that in group A (1.88 ± 0.96; P < .01). Evaluation of graft stenosis with the diastolic-to-systolic peak velocity ratio revealed a sensitivity of 86% and a specificity of 88%. The mean blood flow rate at baseline in group B (16.9 mL/min ± 5.5) was significantly lower than that in group A (79.8 mL/min ± 38.2; P < .01). The sensitivity and specificity of MR blood flow measurement in predicting significant stenosis were 86% and 94%, respectively. The mean pharmacologic flow reserve ratios were 2.00 ± 1.43 in group A and 1.39 ± 1.46 in group B (P > .05).

CONCLUSION: Fast MR blood flow measurement at baseline is highly useful for predicting significant stenosis in internal mammary arterial grafts.

Index terms: Arteries, MR, 54.121416, 54.12144, 949.129416, 949.12944 • Arteries, stenosis or obstruction, 949.721 • Coronary vessels, flow dynamics, 54.91, 949.91 • Coronary vessels, MR, 54.121416, 949.129416 • Magnetic resonance (MR), flow studies, 54.121416, 54.12144, 949.129416, 949.12944 • Stents and prostheses, 949.1268




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