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(Radiology. 2001;220:548-553.)
© RSNA, 2001


Technical Developments

Standardized Perfusion Value: Universal CT Contrast Enhancement Scale that Correlates with FDG PET in Lung Nodules1

Kenneth A. Miles, MD, Matthew R. Griffiths, MAppSc and Melanie A. Fuentes, MBBS

1 From the Southern X-ray Clinics (K.A.M., M.A.F.), and Wesley Research Institute (M.R.G., M.A.F.), Wesley Hospital, 451 Coronation Dr, 2nd Fl, Day Center, Auchenflower, Queensland 4066, Australia; and Center for Medical and Health Physics, School of Physical Sciences, Queensland University of Technology, Brisbane, Australia (K.A.M., M.R.G.). Received August 10, 2000; revision requested October 3; revision received January 5, 2001; accepted January 31. Address correspondence to K.A.M. (e-mail: kenmiles@ozemail.com.au).

The standardized enhancement value and standardized perfusion value allow comparison between different methods for quantification of contrast enhancement during computed tomography (CT). Standard perfusion values calculated from CT measurements of perfusion within pulmonary nodules compared favorably with those derived from previously reported enhancement data and correlated with standardized uptake values obtained from positron emission tomographic images (r = 0.8, P < .01).

Index terms: Computed tomography (CT), comparative studies, 60.12119 • Computed tomography (CT), perfusion study, 60.12119, 60.12163 • Lung, CT, 60.12112, 60.12115 • Lung, nodule, 60.281 • Lung neoplasms, CT, 60.12112, 60.12115 • Lung neoplasms, diagnosis, 60.30 • Lung neoplasms, PET, 60.12163, 60.30 • Positron emission tomography (PET), comparative studies, 60.12163




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