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Diffuse Desmoplastic Breast Carcinoma Metastases to the Liver Simulating Cirrhosis at MR Imaging: Report of Two Cases¹

¹ From the Departments of Radiology (A.B.N., D.G.M.) and Pathology (R.R., E.W.), Thomas Jefferson University Hospital, 132 S 10th St, 1096 Main Bldg, Philadelphia, PA 19107. Received November 3, 2000; revision requested December 23; revision received March 16, 2001; accepted April 9. Address correspondence to D.G.M. (e-mail: donald.mitchell@mail.tju.edu).

Two patients with breast carcinoma, without a prior diagnosis of liver lesions, had proved desmoplastic hepatic metastases that resembled cirrhosis at magnetic resonance (MR) imaging. The cirrhotic appearance of the livers may have resulted from the hepatotoxic effects of chemotherapy and/or hepatic infiltration by the metastatic tumor itself. Despite its high soft-tissue contrast, MR imaging may fail to depict extensive metastases from breast carcinoma, especially when they simulate other diseases (eg, cirrhosis). Correlation of MR imaging findings with clinical history is mandatory.

Index terms: Breast neoplasms, metastases, 00.32 • Liver, MR, 761.121411, 761.121412 • Liver neoplasms, metastases, 761.33

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