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1 From the Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710 (E.F.P., P.C.G.); and the Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH (W.C.B.). Received October 12, 2000; revision requested October 24; revision received November 21; accepted December 9. Address correspondence to E.F.P. (e-mail: patz0002@mc.duke.edu).
Lung cancer continues to be a major worldwide health problem. Multiple strategies are being explored in an attempt to reduce lung cancer mortality, including a renewed interest in screening. Multiple low-dose spiral computed tomography (CT) trials have been proposed, as proponents predict that small nodules will represent early-stage disease and detecting them will ultimately translate into improvements in outcomes. At this time, however, only prevalence-screening data are available, and it remains to be seen if CT will truly reduce mortality. The appropriate hypothesis-driven studies still must be performed and the results carefully analyzed before CT screening for lung cancer can be accepted as the standard of care.
Index terms: Computed tomography (CT), utilization • Lung neoplasms, CT, 60.12111, 60.12115 • Lung neoplasms, diagnosis, 60.32 • Lung neoplasms, screening • Lung neoplasms, staging
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