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Experimental Studies |
1 From the Departments of Radiology (H.J.P.), Urology (D.A.D., J.G.B., A.A.), Biostatistics (J.D., D.Z.), and Orthopaedic Surgery (D.Z.), Childrens Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115. From the 2000 RSNA scientific assembly. Received August 14, 2000; revision requested September 26; final revision received June 25, 2001; accepted August 1. Address correspondence to H.J.P. (e-mail: harriet.paltiel@tch.harvard.edu).
PURPOSE: To compare the accuracy and precision of orchidometer and ultrasonographic (US) measurements of testicular volume in a canine model.
MATERIALS AND METHODS: Volume measurements of 18 canine testes were obtained by using Prader and Rochester orchidometers. Testes were scanned with two linear-array US transducers with imaging frequencies of 613 MHz and 510 MHz. For each transducer, testicular volumes were calculated by using three formulas: length (L) x width (W) x height (H) x 0.52, L x W2 x 0.52, and L x W x H x 0.71. Testes were weighed following bilateral orchiectomies. True testicular volume was determined by using the formula volume = weight/density. Paired t tests were used to assess whether mean measurement biases differed significantly from zero. The relationship between true and measured volume was evaluated with a linear regression model.
RESULTS: US volume measurements demonstrated lower variability and better linear fit compared with orchidometry (R2 = 0.750.90 vs R2 = 0.140.38). The formula L x W x H x 0.71 had the smallest mean bias relative to true volume with use of either transducer over the entire volume range.
CONCLUSION: US methods of testicular volume measurement are more accurate and precise than orchidometry. The formula L x W x H x 0.71 provides a superior estimate of testicular volume and should be used in clinical practice.
Index terms: Animals Experimental study Testis, US, 84.12989 Ultrasound (US), experimental studies, 84.12989
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