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Published online before print November 12, 2001, 10.1148/radiol.2221010190
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(Radiology 2002;222:278-283.)
© RSNA, 2001

Technical Developments

Liver: Single Breath-hold Dynamic Subtraction CT with Multi–Detector Row Helical Technology—Feasibility Study1

Audrey L. Spielmann, MD, Rendon C. Nelson, MD, Carolyn R. Lowry, BSRT(R)(CT), G. Allan Johnson, PhD, Gopal Sundaramoothy, MSEE, Douglas H. Sheafor, MD and Erik K. Paulson, MD

1 From the Department of Radiology, Vancouver Hospital and Health Science Center, Vancouver, British Columbia, Canada (A.L.S.); Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710 (R.C.N., C.R.L., G.A.J., D.H.S., E.K.P.); Department of Radiology, Northeast Medical Center, Concord, NC (D.H.S.); and GE Medical Systems, Milwaukee, Wis (G.S.). Received December 27, 2000; revision requested January 26, 2001; revision received July 9; accepted July 27. Address correspondence to R.C.N. (e-mail: nelso017@mc.duke.edu).

Fifty-two patients with known or suspected hypervascular malignancy were examined to determine the technical feasibility of performing single-breath-hold dynamic subtraction computed tomography (CT) of the liver with multi–detector row helical CT. The precontrast and hepatic arterial CT scans, which were acquired during the same breath hold, were subtracted. The mean liver-to-muscle contrast ratio on the precontrast, hepatic arterial, and subtracted images was 1.3, 1.4, and 2.3, respectively. In 13 patients with lesions, the subtracted images showed a 2.5-fold increase in mean lesion contrast compared with the hepatic arterial CT scans.

Index terms: Computed tomography (CT), helical, 761.12115 • Liver, CT, 761.12114, 761.12115




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