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Published online before print January 11, 2002, 10.1148/radiol.2222010249
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(Radiology 2002;222:555-559.)
© RSNA, 2002


Technical Developments

Intrathecal Gadolinium-enhanced MR Cisternography in the Evaluation of Clinically Suspected Cerebrospinal Fluid Rhinorrhea in Humans: Early Experience1

J. Randy Jinkins, MD, Mohamed Rudwan, MD, Gaida Krumina, MD, PhD and E. Turgut Tali, MD

1 From the Department of Radiological Sciences, Medical College of Pennsylvania-Hahnemann University, 245 N 15th St, Mailstop 206, Philadelphia, PA 19102-1192 (J.R.J.); Department of Radiology, Ibn Sina Hospital, Kuwait City, Kuwait (M.R.); Radiology Clinic, Education and Research Center, Riga, Latvia (G.K.); and Department of Radiology, Gazi University School of Medicine, Ankara, Turkey (E.T.T.). Received January 9, 2001; revision requested February 28; revision received April 20; accepted May 21. Address correspondence to J.R.J. (e-mail: jrjinkins@aol.com).

In this prospective multicenter study, the authors evaluated the utility of magnetic resonance (MR) cisternography after intrathecal administration of gadopentetate dimeglumine in 15 patients clinically suspected of having cerebrospinal fluid (CSF) rhinorrhea. By means of lumbar puncture, a single dose of 0.5 mL of gadopentetate dimeglumine was injected into the lumbar subarachnoid space. Thirteen patients showed leakage of contrast material through the cribriform plate into the ethmoid or sphenoid air cells. No leakage was observed in two patients. The study results show the relative safety and feasibility of low-dose gadolinium-enhanced MR cisternography in confirming the presence and determining the focus of active CSF leaks.

Index terms: Cerebrospinal fluid, leakage, 121.423, 167.423 • Cisternography, MR, 121.12143, 167.12175 • Fistula, cerebrospinal, 121.24, 167.24 • Magnetic resonance (MR), contrast media, 167.12143




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