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Published online before print December 2, 2002, 10.1148/radiol.2261011708
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(Radiology 2003;226:256-262.)
© RSNA, 2002


Technical Developments

Lung Micronodules: Automated Method for Detection at Thin-Section CT—Initial Experience1

Matthew S. Brown, PhD, Jonathan G. Goldin, MD, PhD, Robert D. Suh, MD, Michael F. McNitt-Gray, PhD, James W. Sayre, PhD and Denise R. Aberle, MD

1 From the Department of Radiology, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095-1721. Received October 18, 2001; revision requested January 11, 2002; revision received March 11; accepted May 7, 2002. Address correspondence to M.S.B. (e-mail: mbrown@mednet.ucla.edu).

An automated system was developed for detecting lung micronodules on thin-section computed tomographic images and was applied to data from 15 subjects with 77 lung nodules. The automated system, without user interaction, achieved a sensitivity of 100% for nodules (>3 mm in diameter) and 70% for micronodules (<=3 mm). With the same images, a radiologist detected nodules and micronodules with sensitivities of 91% and 51%, respectively, without system input. With assistance from the automated system, these sensitivities increased to 95% and 74%, respectively. Preliminary results indicate that the automated system considerably improved the radiologist’s performance in micronodule detection.

© RSNA, 2002

Index terms: Computed tomography (CT), computer programs • Computed tomography (CT), image processing • Computers, diagnostic aid • Lung, nodule, 60.281




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