| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gastrointestinal Imaging |
1 From the Department of Radiology, Hôpital Beaujon and Laboratoire d’Imagerie Médicale Paris-Nord, Faculté de Médecine Paris VII, Clichy, France (B.T., V.V., E.D., J.L.D., Y.M.); and Department of Radiology, University of California San Francisco, 505 Parnassus Ave, Rm M-372, Box 0628, San Francisco, CA 94143 (B.T., B.F.). From the 2001 RSNA scientific assembly. Received November 27, 2001; revision requested February 7, 2002; revision received March 15; accepted May 7. Supported by a grant from the French Radiology Society. Address correspondence to B.T. (e-mail: bachir.taouli@radiology.ucsf.edu).
PURPOSE: To (a) evaluate liver diffusion isotropy, (b) compare two diffusion-weighted magnetic resonance (MR) imaging sequences for the characterization of focal hepatic lesions by using two or four b values, and (c) determine an apparent diffusion coefficient (ADC) threshold value to differentiate benign from malignant lesions.
MATERIALS AND METHODS: Sixty-six patients were examined with two single-shot echo-planar diffusion-weighted MR sequences. In the first sequence, liver diffusion isotropy was evaluated by using diffusion gradients in three directions with two b values. In the second sequence, a unidirectional diffusion gradient was used with four b values. ADCs were measured in 43 patients with 52 focal hepatic lesions more than 1 cm in diameter and in 23 patients with 14 normal and nine cirrhotic livers and were compared by using nonparametric tests.
RESULTS: Diffusion in the liver parenchyma was isotropic. ADCs of focal hepatic lesions were significantly different between sequences (P < .01). The mean (± SD) ADCs in the first sequence were 0.94 x 10-3 mm2/sec ± 0.60 for metastases, 1.33 x 10-3 mm2/sec ± 0.13 for HCCs, 1.75 x 10-3 mm2/sec ± 0.46 for benign hepatocellular lesions, 2.95 x 10-3 mm2/sec ± 0.67 for hemangiomas, and 3.63 x 10-3 mm2/sec ± 0.56 for cysts. There was a significant difference between benign (2.45 x 10-3 mm2/sec ± 0.96, isotropic value) and malignant (1.08 x 10-3 mm2/sec ± 0.50) lesions (P < .01 for both sequences).
CONCLUSION: Diffusion-weighted MR imaging can help differentiate benign from malignant hepatic lesions. The use of two b values in one direction could be sufficient for the design of MR sequences in the liver.
© RSNA, 2002
Index terms: Liver, diseases, 761.30, 761.79 • Liver, focal nodular hyperplasia, 761.3198 • Liver neoplasms, 761.30 • Liver neoplasms, MR, 761.121416, 761.12144 • Magnetic resonance (MR), diffusion study, 761.12144 • Magnetic resonance (MR), echo planar, 761.121416
This article has been cited by other articles:
|
|
 |
|
  Y. Cui, X.-P. Zhang, Y.-S. Sun, L. Tang, and L. Shen Apparent Diffusion Coefficient: Potential Imaging Biomarker for Prediction and Early Detection of Response to Chemotherapy in Hepatic Metastases Radiology, September 1, 2008; 248(3): 894 - 900. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. I. Sainani, O. A. Catalano, N.-S. Holalkere, A. X. Zhu, P. F. Hahn, and D. V. Sahani Cholangiocarcinoma: Current and Novel Imaging Techniques RadioGraphics, September 1, 2008; 28(5): 1263 - 1287. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. C. van den Bos, S. M. Hussain, G. P. Krestin, and P. A. Wielopolski Liver Imaging at 3.0 T: Diffusion-induced Black-Blood Echo-planar Imaging with Large Anatomic Volumetric Coverage as an Alternative for Specific Absorption Rate-intensive Echo-Train Spin-Echo Sequences: Feasibility Study Radiology, July 1, 2008; 248(1): 264 - 271. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Zhang, Y. Mazaheri Tehrani, L. Wang, N. M. Ishill, L. H. Schwartz, and H. Hricak Renal Masses: Characterization with Diffusion-weighted MR Imaging--A Preliminary Experience Radiology, May 1, 2008; 247(2): 458 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Hanna, D. A. Aguirre, N. Kased, S. C. Emery, M. R. Peterson, and C. B. Sirlin Cirrhosis-associated Hepatocellular Nodules: Correlation of Histopathologic and MR Imaging Features RadioGraphics, May 1, 2008; 28(3): 747 - 769. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. G. Lall, A. M. Aisen, N. Bansal, and K. Sandrasegaran Nonalcoholic Fatty Liver Disease Am. J. Roentgenol., April 1, 2008; 190(4): 993 - 1002. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Parikh, S. J. Drew, V. S. Lee, S. Wong, E. M. Hecht, J. S. Babb, and B. Taouli Focal Liver Lesion Detection and Characterization with Diffusion-weighted MR Imaging: Comparison with Standard Breath-hold T2-weighted Imaging Radiology, March 1, 2008; 246(3): 812 - 822. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-H. Shen, Y.-Y. Chiou, J.-H. Wang, M.-S. Yen, R.-C. Lee, C.-R. Lai, and C.-Y. Chang Diffusion-Weighted Single-Shot Echo-Planar Imaging with Parallel Technique in Assessment of Endometrial Cancer Am. J. Roentgenol., February 1, 2008; 190(2): 481 - 488. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Inan, A. Arslan, G. Akansel, Y. Anik, H. T. Sarisoy, E. Ciftci, and A. Demirci Diffusion-Weighted Imaging in the Differential Diagnosis of Simple and Hydatid Cysts of the Liver Am. J. Roentgenol., November 1, 2007; 189(5): 1031 - 1036. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Taouli, A. J. Tolia, M. Losada, J. S. Babb, E. S. Chan, M. A. Bannan, and H. Tobias Diffusion-Weighted MRI for Quantification of Liver Fibrosis: Preliminary Experience Am. J. Roentgenol., October 1, 2007; 189(4): 799 - 806. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D.-M. Koh and D. J. Collins Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology Am. J. Roentgenol., June 1, 2007; 188(6): 1622 - 1635. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Matoba, H. Tonami, T. Kondou, H. Yokota, K. Higashi, H. Toga, and T. Sakuma Lung Carcinoma: Diffusion-weighted MR Imaging--Preliminary Evaluation with Apparent Diffusion Coefficient Radiology, May 1, 2007; 243(2): 570 - 577. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D.-M. Koh, E. Scurr, D. Collins, B. Kanber, A. Norman, M. O. Leach, and J. E. Husband Predicting Response of Colorectal Hepatic Metastasis: Value of Pretreatment Apparent Diffusion Coefficients Am. J. Roentgenol., April 1, 2007; 188(4): 1001 - 1008. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Yoshikawa, H. Kawamitsu, D. G. Mitchell, Y. Ohno, Y. Ku, Y. Seo, M. Fujii, and K. Sugimura ADC measurement of abdominal organs and lesions using parallel imaging technique. Am. J. Roentgenol., December 1, 2006; 187(6): 1521 - 1530. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-Y. Chen, C.-W. Li, Y.-T. Kuo, T.-S. Jaw, D.-K. Wu, J.-C. Jao, J.-S. Hsu, and G.-C. Liu Early Response of Hepatocellular Carcinoma to Transcatheter Arterial Chemoembolization: Choline Levels and MR Diffusion Constants--Initial Experience Radiology, May 1, 2006; 239(2): 448 - 456. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. C. Thoeny, F. De Keyzer, R. H. Oyen, and R. R. Peeters Diffusion-weighted MR Imaging of Kidneys in Healthy Volunteers and Patients with Parenchymal Diseases: Initial Experience Radiology, June 1, 2005; 235(3): 911 - 917. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. C. Thoeny, F. De Keyzer, F. Chen, Y. Ni, W. Landuyt, E. K. Verbeken, H. Bosmans, G. Marchal, and R. Hermans Diffusion-weighted MR Imaging in Monitoring the Effect of a Vascular Targeting Agent on Rhabdomyosarcoma in Rats Radiology, March 1, 2005; 234(3): 756 - 764. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Taouli, A. J. Martin, A. Qayyum, R. B. Merriman, D. Vigneron, B. M. Yeh, and F. V. Coakley Parallel Imaging and Diffusion Tensor Imaging for Diffusion-Weighted MRI of the Liver: Preliminary Experience in Healthy Volunteers Am. J. Roentgenol., September 1, 2004; 183(3): 677 - 680. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Kamel, D. A. Bluemke, D. Ramsey, M. Abusedera, M. Torbenson, J. Eng, G. Szarf, and J.-F. Geschwind Role of Diffusion-Weighted Imaging in Estimating Tumor Necrosis After Chemoembolization of Hepatocellular Carcinoma Am. J. Roentgenol., September 1, 2003; 181(3): 708 - 710. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| RADIOLOGY | RADIOGRAPHICS | RSNA JOURNALS ONLINE |
