HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: 2272020173v1 227/2/493    most recent Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Laeseke, P. F. Articles by Lee, F. T. Search for Related Content PubMed PubMed Citation Articles by Laeseke, P. F. Articles by Lee, F. T., Jr

Postbiopsy Bleeding in a Porcine Model: Reduction with Radio-frequency Ablation—Preliminary Results¹

¹ From the Departments of Biomedical Engineering (P.F.L., K.R.S., F.J.F., J.G.W.) and Radiology (T.C.W., C.D.J., F.T.L.), University of Wisconsin-Madison Medical School, CSC-Module E3-311, Box 3252, 600 Highland Ave, Madison, WI 53792; and Department of Medicine, University of Washington, Seattle (C.L.D.). From the 2001 RSNA scientific assembly. Received February 28, 2002; revision requested April 24; final revision received September 17; accepted September 24. Address correspondence to T.C.W. (e-mail: tcwinter@wisc.edu).

PURPOSE: To test a biopsy needle modified for use of radio-frequency (RF) energy to produce hemostasis after core biopsy of liver or kidney.

MATERIALS AND METHODS: RF energy was applied to a partially insulated 17-gauge needle, and tip temperature was monitored with a thermocouple. Domestic Yorkshire pigs (n = 4; mean weight, 23.4 kg) were anesthetized, and their livers and kidneys were exposed. Needles were inserted 2 cm into hepatic and renal parenchyma and retracted, either with or without tract ablation to 65°C, in normal tissue, animals treated with anticoagulants, and an animal with acute inferior vena caval occlusion to produce portal hypertension. Blood loss was assessed by weighing surgical sponges with blood from the puncture sites. Significant differences in blood loss between control and ablated biopsy specimens in each scenario were tested by using a Wilcoxon matched-pairs signed rank test.

RESULTS: Mean blood loss for each group was as follows: In the liver, control biopsy specimens (n = 18) lost 0.30 g while ablated biopsy specimens lost 0.00044 g (P < .01), and control biopsy specimens treated with heparin (n = 26) lost 0.45 g while biopsy specimens treated with heparin and ablation lost 0.27 g (P = .03). For inferior vena caval occlusion, control biopsy specimens lost 1.23 g, while ablated biopsy specimens lost 0.00 g. In the kidney, control biopsy specimens (n = 28) lost 0.82 g, while ablated biopsy specimens lost 0.24 g (P = .01), and control biopsy specimens treated with heparin (n = 14) lost 1.04 g, while biopsy specimens treated with heparin and ablation lost 0.19 g (P = .02).

CONCLUSION: Tract ablation with thermocouple-monitored RF energy decreased postprocedural hemorrhage after hepatic and renal biopsy.

© RSNA, 2003

Index terms: Animals • Biopsies, technology, 761.1261, 81.1261 • Experimental study, 761.1261, 81.1261 • Kidney, biopsy, 81.1261 • Liver, biopsy, 761.1261 • Radiofrequency (RF) ablation, 761.1261, 81.1261

This article has been cited by other articles:

				S. H. Choi, J. M. Lee, K. H. Lee, S. H. Kim, J. Y. Lee, J. K. Han, and B. I. Choi Postbiopsy Splenic Bleeding in a Dog Model: Comparison of Cauterization, Embolization, and Plugging of the Needle Tract Am. J. Roentgenol., October 1, 2005; 185(4): 878 - 884. [Abstract] [Full Text] [PDF]

				S. A. Shock, P. F. Laeseke, L. A. Sampson, W. D. Lewis, T. C. Winter III, J. P. Fine, and F. T. Lee Jr Hepatic Hemorrhage Caused by Percutaneous Tumor Ablation: Radiofrequency Ablation versus Cryoablation in a Porcine Model Radiology, July 1, 2005; 236(1): 125 - 131. [Abstract] [Full Text] [PDF]