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Published online before print May 15, 2003, 10.1148/radiol.2281020606
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(Radiology 2003;228:257-264.)
© RSNA, 2003


Technical Developments

Can Noise Reduction Filters Improve Low-Radiation-Dose Chest CT Images? Pilot Study1

Mannudeep K. Kalra, MD, Conrad Wittram, MB, ChB, Michael M. Maher, MD, FFR (RCSI), FRCR, Amita Sharma, MD, Gopal B. Avinash, PhD, Kelly Karau, PhD, Thomas L. Toth, AAS, Elkan Halpern, PhD, Sanjay Saini, MD and Jo-Anne Shepard, MD

1 From the Department of Radiology, Founders 202, Massachusetts General Hospital and Harvard Medical School, 32 Fruit St, Boston, MA 02114 (M.K.K., C.W., M.M.M., A.S., E.H., S.S., J.S.), and GE Medical Systems, Waukesha, Wis (G.B.A., K.K., T.L.T.). Supported in part by a grant from GE Medical Systems. Received May 23, 2002; revision requested July 16; final revision received October 11; accepted October 23. Address correspondence to J.S. (e-mail: jshepard@partners.org).

Effect of noise reduction filters on chest computed tomographic (CT) images acquired with 50% radiation dose reduction was evaluated. Two sets of images were acquired with multi–detector row CT at standard (220–280 mA) and 50% reduced (110–140 mA) tube current at the level of the carina. After postprocessing with six noise reduction filters, images were compared with baseline standard-dose images for noise, sharpness, and contrast in lungs, mediastinum, and chest wall. Quantitative image noise was measured in descending thoracic aorta. Modulation transfer functions were calculated from CT images of 50-µm wire. Noise reduction filters reduced image noise on low-radiation-dose chest CT images, with some compromise in image sharpness and contrast assessed qualitatively, and slightly altered modulation transfer function at higher spatial frequencies.

© RSNA, 2003

Index terms: Computed tomography (CT), radiation exposure • Filters, radiographic • Thorax, CT, 60.12112, 60.12115




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