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DOI: 10.1148/radiol.2302030360
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(Radiology 2004;230:553-555.)
© RSNA, 2004


Breast Imaging

Screening-detected Breast Cancer in a Man with BRCA2 Mutation: Case Report1

R. James Brenner, MD, Jeffrey N. Weitzel, MD, Nora Hansen, MD and Peter Boasberg, MD

1 From the Eisenberg Keefer Breast Center (R.J.B.), Department of Surgical Oncology (N.H.), and Department of Medical Oncology (P.B.), John Wayne Cancer Institute, Saint Johns Health Center, 1328 22nd St, Santa Monica, CA 90404; Department of Radiologic Science, UCLA-Geffen School of Medicine, Los Angeles, Calif (R.J.B.); and Department of Clinical Cancer Genetics, City of Hope Cancer Center, Duarte, Calif (J.N.W.). Received February 28, 2003; revision requested May 7; revision received June 10; accepted July 23. Address correspondence to R.J.B. (e-mail: james.brenner@stjohns.org).

Current indications for breast cancer screening in the male population are lacking, although family history of breast cancer may be such an indication. The authors describe a man with a history of clinically diagnosed right breast cancer who subsequently tested positive for the breast cancer susceptibility gene BRCA2 and received a diagnosis of mammographically detected left breast cancer at screening. The authors discuss the clinical implications of this approach to detecting male breast cancer.

© RSNA, 2004

Index terms: Breast neoplasms, male, 00.32 • Cancer screening • Genes and genetics







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