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DOI: 10.1148/radiol.2312030606
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(Radiology 2004;231:571-580.)
© RSNA, 2004

Technical Developments

Electromagnetic Breast Imaging: Average Tissue Property Values in Women with Negative Clinical Findings1

Steven P. Poplack, MD, Keith D. Paulsen, PhD, Alexander Hartov, PhD, Paul M. Meaney, PhD, Brian W. Pogue, PhD, Tor D. Tosteson, ScD, Margaret R. Grove, MS, Sandra K. Soho, RN and Wendy A. Wells, MD

1 From the Depts of Radiology (S.P.P.), Obstetrics and Gynecology (S.K.S.), and Pathology (W.A.W.), Dartmouth Hitchcock Med Ctr, One Medical Center Dr, Lebanon, NH 03756; Thayer School of Engineering, Dartmouth College, Hanover, NH (K.D.P., A.H., P.M.M., B.W.P.); and Dept of Community and Family Medicine, Norris Cotton Cancer Ctr, Lebanon, NH (T.D.T., M.R.G.). Received Apr 10, 2003; revision requested Jun 27; revision received Sep 8; accepted Oct 14. Supported by National Institutes of Health grant P01-CA80139. Address correspondence to S.P.P. (e-mail: steven.p.poplack@hitchcock.org).

Representative data are provided for three electromagnetic breast imaging techniques—near-infrared spectroscopy, electrical impedance spectroscopy, and microwave imaging spectroscopy—to serve as potential benchmarks for future investigation. The breasts of 23 women without clinical or mammographic findings of disease were imaged in the coronal plane with nonionizing radiation of varying frequencies. Average electromagnetic property values were reconstructed at each frequency on the basis of computational models of light diffusion, current flow, and microwave propagation. Electromagnetic properties were correlated with subject characteristics and between techniques. Each technique yielded information on breast tissue features (eg, conductivity, permittivity, light scattering, and absorption) that had not previously all been measured in the same individuals.

© RSNA, 2004

Index terms: Breast, 00.1299 • Infrared and near-infrared spectroscopy, 00.1299




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