| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Technical Developments |
1 From the Departments of Radiology (S.M.K., J.D.E.) and Community and Family Medicine (D.M.D.), Duke University Medical Center, Box 3808, Durham, NC 27710; and School of Medicine, University of Pennsylvania, Philadelphia (V.A.L.). Received March 27, 2003; revision requested June 18; final revision received September 16; accepted October 8. Address correspondence to S.M.K. (e-mail: susankealey@hotmail.com).
The authors reviewed 40 computed tomographic (CT) perfusion studies to determine the effect of arterial and venous input function properties on perfusion parameter values and tissue signal-to-noise ratio (SNR). A 10-subject subset was analyzed to evaluate the effect of varying venous region of interest (ROI) locations. Venous peak enhancement correlated significantly with mean tissue cerebral blood flow (CBF) and cerebral blood volume (CBV); venous and arterial peak enhancement correlated significantly with SNR of perfusion maps. Different ROI locations within the same vein resulted in significantly different CBV and CBF values. Perfusion map parameters are related to peak enhancement within user-selected ROIs. Optimal ROI selection should limit variability and increase quality of CT perfusion images.
© RSNA, 2004
Index terms: Brain, perfusion • Computed tomography (CT), perfusion study, 14.12112
This article has been cited by other articles:
|
|
 |
|
  A.S. Vagal, J.L. Leach, M. Fernandez-Ulloa, and M. Zuccarello The Acetazolamide Challenge: Techniques and Applications in the Evaluation of Chronic Cerebral Ischemia AJNR Am. J. Neuroradiol., May 1, 2009; 30(5): 876 - 884. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Kudo, M. Sasaki, K. Ogasawara, S. Terae, S. Ehara, and H. Shirato Difference in Tracer Delay-induced Effect among Deconvolution Algorithms in CT Perfusion Analysis: Quantitative Evaluation with Digital Phantoms Radiology, April 1, 2009; 251(1): 241 - 249. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Goh, S. Halligan, A. Gharpuray, D. Wellsted, J. Sundin, and C. I. Bartram Quantitative Assessment of Colorectal Cancer Tumor Vascular Parameters by Using Perfusion CT: Influence of Tumor Region of Interest Radiology, June 1, 2008; 247(3): 726 - 732. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.M. Silvennoinen, L.M. Hamberg, L. Valanne, and G.J. Hunter Increasing Contrast Agent Concentration Improves Enhancement in First-Pass CT Perfusion AJNR Am. J. Neuroradiol., August 1, 2007; 28(7): 1299 - 1303. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Waaijer, I.C. van der Schaaf, B.K. Velthuis, M. Quist, M.J.P. van Osch, E.P.A. Vonken, M.S. van Leeuwen, and M. Prokop Reproducibility of Quantitative CT Brain Perfusion Measurements in Patients with Symptomatic Unilateral Carotid Artery Stenosis AJNR Am. J. Neuroradiol., May 1, 2007; 28(5): 927 - 932. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B.D. Murphy, X. Chen, and T.-Y. Lee Serial Changes in CT Cerebral Blood Volume and Flow after 4 Hours of Middle Cerebral Occlusion in an Animal Model of Embolic Cerebral Ischemia AJNR Am. J. Neuroradiol., April 1, 2007; 28(4): 743 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Provenzale, S. Mukundan, and D. P. Barboriak Diffusion-weighted and Perfusion MR Imaging for Brain Tumor Characterization and Assessment of Treatment Response. Radiology, June 1, 2006; 239(3): 632 - 649. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. van der Schaaf, E.-J. Vonken, A. Waaijer, B. Velthuis, M. Quist, and T. van Osch Influence of Partial Volume on Venous Output and Arterial Input Function AJNR Am. J. Neuroradiol., January 1, 2006; 27(1): 46 - 50. [Abstract] [Full Text] [PDF]
|
|
