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Technical Developments |
1 From the Imaging Science Laboratories (V.M., V.V.I., M.S., J.G.S.A., D.D.S., G.M., Z.A.F.); the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Cardiovascular Health Center, and Department of Medicine (V.M., J.G.S.A., G.M., Z.A.F.); and Department of Radiology (V.V.I., D.D.S., Z.A.F.); Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1234, New York, NY 10029-6574; and Siemens Medical Solutions, Malvern, Pa (M.S.). Received July 1, 2003; revision requested August 29; revision received October 17; accepted November 24. Supported in part by NIH/NHLBI ROI HL71021, the Howard Hughes Medical Institute Biomedical Research Support Program Grant, the Herman Goldman Foundation, the New York Community Trust, the Mount Sinai Consortium for Cardiovascular Imaging Technology, the Eva and Morris Feld Estate, the Louis B. Mayer Foundation, the Peter Jay Sharp Foundation, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Cardiovascular Health Center, and the Dept of Radiology, Mount Sinai School of Medicine. Address correspondence to Z.A.F. (e-mail: zahi.fayad@mssm.edu).
A two-dimensional rapid extended coverage (REX) rapid acquisition with relaxation enhancement (RARE) pulse sequence for simultaneous multisection double inversion-recovery (DIR) black-blood vessel wall magnetic resonance (MR) imaging was developed. Aortic vessel wall MR imaging was performed in five healthy subjects (mean age, 33 years ± 4 [SD]) and five patients with atherosclerotic disease (mean age, 67 years ± 11.7). Shortening of blood inversion time and imaging of multiple sections after single DIR block resulted in simultaneous acquisition of up to 20 aortic wall sections in less than 1 minute (spatial resolution, 0.97 x 0.97 x 3 mm3). Higher signal-to-noise ratios per unit time per section (16.0 ± 2.45 vs 7.5 ± 1.10, P < .05), no significant changes in contrast-to-noise ratios (15.0 ± 5.3 vs 20.1 ± 3.9, P > .05), and 17-fold improvement in acquisition time compared with those at conventional single-section DIR RARE imaging was achieved. Use of the REX method significantly shortened aortic imaging acquisition times without degrading image quality.
© RSNA, 2004
Index terms: Aorta, diseases, 563.75 • Aorta, MR, 563.121413, 563.121416 • Magnetic resonance (MR), pulse sequences • Magnetic resonance (MR), rapid imaging • Magnetic resonance (MR), technology
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