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DOI: 10.1148/radiol.2321030383
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(Radiology 2004;232:295-301.)
© RSNA, 2004

Technical Developments

Emphysema: Effect of Reconstruction Algorithm on CT Imaging Measures1

Kirsten L. Boedeker, MS, Michael F. McNitt-Gray, PhD, Sarah R. Rogers, MS, Dao A. Truong, BS, Matthew S. Brown, PhD, David W. Gjertson, PhD and Jonathan G. Goldin, MD, PhD

1 From the Department of Radiology, David Geffen School of Medicine, University of California at Los Angeles, 10833 Le Conte Ave, CHS B3–227U, Box 951721, Los Angeles, CA 90095-1721. Received March 10, 2003; revision requested May 28; revision received August 29; accepted October 8. Supported in part by National Heart, Lung, and Blood Institute grant N01-HR96143. Address correspondence to K.L.B. (e-mail: kboedeker@mednet.ucla.edu).

In the current study, the effects of reconstruction algorithms on quantitative measures derived from computed tomographic (CT) lung images were assessed in patients with emphysema. CT image data sets were reconstructed with a standard algorithm and alternative algorithm(s) for 42 subjects. Algorithms were grouped as overenhancing, sharp, standard, or smooth. Density mask and volume measurements from the alternative algorithm data sets were compared with standard algorithm data sets. The overenhancing category yielded an average shift of 9.4% (ie, a shift in average score from 35.5% to 44.9%); the sharp category, a shift of 2.4%; and the smooth category, a shift of –1.0%. Differences in total lung volume measurements were less than 1%. In conclusion, the CT reconstruction algorithm may strongly affect density mask results, especially for certain reconstruction algorithms.

© RSNA, 2004

Index terms: Computed tomography (CT), computer programs, 60.12115, 60.12118 • Computed tomography (CT), electron beam, 60.12118 • Computed tomography (CT), image processing, 60.12115, 60.12118 • Emphysema, pulmonary, 60.751 • Lung, CT, 60.12115, 60.12118




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