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Published online before print June 23, 2004, 10.1148/radiol.2322030334
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(Radiology 2004;232:606-610.)
© RSNA, 2004

Technical Developments

Acute Myocardial Infarction: Tissue Characterization with T1{rho}-weighted MR Imaging—Initial Experience1

Raja Muthupillai, PhD, Scott D. Flamm, MD, James M. Wilson, MD, Roderic I. Pettigrew, MD, PhD and W. Thomas Dixon, PhD2

1 From Philips Medical Systems, Cleveland, Ohio (R.M.); Departments of Radiology (R.M., S.D.F.) and Cardiology (S.D.F., J.M.W.), St Luke’s Episcopal Hospital and Baylor College of Medicine, 6720 Bertner Ave, MC 2–256, Houston, TX 77030; and Department of Radiology, Emory University Hospital, Atlanta, Ga (R.I.P., W.T.D.). Received February 27, 2003; revision requested May 20; final revision received November 25; accepted December 17. W.T.D. and R.I.P. supported by grant no. RO1 HL58417. Address correspondence to R.M. (e-mail: raja.muthupillai@philips.com).

Acute myocardial injury was evaluated in 21 patients by using a contrast material–enhanced T1{rho}-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1{rho}-weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% ± 344). With T1{rho} weighting, percentage enhancement of irreversibly injured myocardium was 68% ± 41, compared with 23% ± 24 without T1{rho} weighting (P < .006). The addition of T1{rho} weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.

© RSNA, 2004

Index terms: Magnetic resonance (MR), cine study, 511.12142, 511.12143 • Magnetic resonance (MR), tissue characterization, 511.12146 • Myocardium, infarction, 511.76, 511.771 • Myocardium, MR, 511.12142, 511.12143, 511.12146




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