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Coronary Artery Calcium Score: Influence of Reconstruction Interval at 16–Detector Row CT with Retrospective Electrocardiographic Gating¹

¹ From the Departments of Diagnostic and Interventional Radiology (T.S., P.H., H.K., K.U.W., J.F.D., J.B.) and Cardiology (A.S.), University Hospital, Hufelandstr 55, 45122 Essen, Germany. Received September 11, 2003; revision requested November 24; final revision received March 12, 2004; accepted April 19. Address correspondence to J.B. (e-mail: joerg.barkhausen@uni-essen.de).

In 30 patients, Agatston and volumetric scores were assessed by using retrospectively gated multi–detector row computed tomography (CT). For each patient, 10 data sets were created at different times and were evenly spaced throughout the cardiac cycle. For each reconstruction, patients were assigned a percentile that described the level of cardiovascular risk. Nineteen (63%) of 30 patients could be assigned to more than one risk group depending on the reconstruction interval used. Agatston and volumetric scores both proved highly dependent on the reconstruction interval used (coefficient of variation, 63.1%) even with the most advanced CT scanners. Accurate and reproducible quantification of coronary calcium seems to require analysis of multiple reconstructions.

© RSNA, 2004

Index terms: Computed tomography (CT), multi–detector row • Coronary vessels, calcification, 54.812 • Coronary vessels, CT, 54.12115 • Coronary vessels, diseases, 54.812

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