HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: 2341040041v1 234/1/245    most recent Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mosher, T. J. Articles by Smith, M. B. Search for Related Content PubMed PubMed Citation Articles by Mosher, T. J. Articles by Smith, M. B.

Change in Knee Cartilage T2 at MR Imaging after Running: A Feasibility Study¹

¹ From the Pennsylvania State University Center for NMR Research, Department of Radiology, Milton S. Hershey Medical Center, 500 University Dr, Hershey, PA 17033 (T.J.M., C.C., Y.L., J.H., M.B.S.); Departments of Radiology, Pediatrics, and Biomedical Engineering, University of Cincinnati, College of Medicine, Imaging Research Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio (B.J.D.); and Department of Orthopedic Surgery, Thomas Jefferson University Hospital, Philadelphia, Pa (H.E.S.). Received January 8, 2004; revision requested March 12; revision received March 25; accepted April 8. T.J.M. and B.J.D. supported by research grants from the Arthritis Foundation and National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. Address correspondence to T.J.M. (e-mail: tmosher@psu.edu).

All participants provided informed consent to participate in this study, which was approved by the institutional review board of Milton S. Hershey Medical Center. The purpose of the study was to determine the feasibility of cartilage T2 mapping in the evaluation of response of femoral and tibial cartilage to running exercise. Quantitative magnetic resonance (MR) T2 maps of weight-bearing femoral and tibial articular cartilage were obtained in seven young healthy men before and immediately after 30 minutes of running by using a 3.0-T MR imager. There was no statistically significant change in T2 profiles of tibial cartilage. There was a statistically significant decrease in T2 of the superficial 40% of weight-bearing femoral cartilage after exercise. These in vivo observations agree well with published ex vivo results and support the hypothesis that cartilage compression results in greater anisotropy of superficial collagen fibers.

© RSNA, 2004

This article has been cited by other articles:

				M. A. Kessler, C. Glaser, S. Tittel, M. Reiser, and A. B. Imhoff Volume Changes in the Menisci and Articular Cartilage of Runners: An In Vivo Investigation Based on 3-D Magnetic Resonance Imaging Am. J. Sports Med., May 1, 2006; 34(5): 832 - 836. [Abstract] [Full Text] [PDF]