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MR Imaging–guided Prostate Biopsy with a Closed MR Unit at 1.5 T: Initial Results¹

¹ From the Departments of Radiology (D.B., B.H., M.T.) and Urology (S.L., S.A.L.), Charité, Humboldt-Universität zu Berlin, Schumannstrasse 20/21, 10117 Berlin, Germany; and MRI Devices/Daum, Schwerin, Germany (A.W.). From the 2002 RSNA Annual Meeting. Received December 1, 2003; revision requested January 4, 2004; revision received March 5; accepted May 10. Supported by Bundes Ministerium für Bildung und Forschung grant no. 01EZ0027. Address correspondence to D.B. (e-mail: dirk.beyersdorff@charite.de).

The authors evaluated a magnetic resonance (MR) imaging–compatible biopsy device comprising a needle guide that can be visualized with MR imaging and manipulated mechanically from outside the MR unit. With approval from the local ethics committee and patient consent, this device was tested in 12 patients by using a closed 1.5-T MR unit and a body phased-array coil. Patients had elevated prostate-specific antigen levels (6–60 ng/mL) and one or more areas in the prostate that were suspicious for carcinoma at prebiopsy MR imaging. Biopsy was performed with transrectal access and with the patient prone. A 16-gauge MR imaging–compatible needle was successfully positioned with the device, and between six and nine tissue cores were obtained in each patient. In one patient, two suspicious basal areas could not be reached with the device. Histologic analysis showed prostate cancer in five patients and prostatitis in six. No complications were observed. The device enabled MR imaging–guided core-needle biopsy of prostate areas suspicious for cancer on MR images.

© RSNA, 2004

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