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Feasibility of Integrating High-Spatial-Resolution 3D Breath-hold Coronary MR Angiography with Myocardial Perfusion and Viability Examinations¹

¹ From the Applied Science Laboratory, GE Healthcare Technologies, Room 110-MRI, 600 N Wolfe St, Baltimore, MD 21287 (T.K.F.F., M.S.); Dept of Radiology and Radiological Sciences, Uniformed Services Univ of the Health Sciences, Bethesda, Md (V.B.H.); Dept of Radiology, Chinese PLA General Hosp, Beijing, China (L.C.); Dept of Radiology, Mie Univ, Tsu, Japan (H.S.); and Dept of Radiology (D.L.K., D.A.B.) and Div of Cardiology (K.C.W.), Johns Hopkins Univ, Baltimore, Md. Received Jan 19, 2004; revision requested Mar 19; final revision received Aug 9; accepted Sep 2. Research grant by GE Healthcare Technologies (V.B.H.) and Bracco Diagnostics (V.B.H., D.A.B.). Address correspondence to T.K.F.F. (e-mail: thomas.foo@med.ge.com).

The study was institutional review board approved and Health Insurance Portability and Accountability Act compliant. All subjects provided informed consent. Three-dimensional breath-hold coronary magnetic resonance (MR) angiography with use of steady-state free precession was performed in 12 patients up to 20 minutes after 0.2 mmol gadolinium-based contrast material per kilogram of body weight was administered. Within 24 heartbeats, a spatial resolution of up to 1.0 x 1.2 x 2.0 mm was achieved. Sixty-five (82%) of the 79 visualized coronary artery segments had a grade of 3 or 4 on a four-point scale of depiction in which grade 4 indicated excellent depiction. Twenty-seven percent (n = 21) of the 79 segments were assigned a grade of 4; 56% (n = 44), a grade of 3; 16% (n = 13), a grade of 2; and 1% (n = 1), a grade of 1. Coronary MR angiography performed as part of a first-pass myocardial perfusion and viability assessment MR imaging examination is feasible and does not involve additional imaging time.

© RSNA, 2005

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