| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Evidence-based Practice |
1 From the Vascular Laboratory (S.S.) and Department of Surgery (H.F.V., P.T.d.H.), Ikazia Hospital, Rotterdam, the Netherlands; Departments of Epidemiology and Biostatistics and Radiology, Erasmus University Medical Center Rotterdam, EE21–40a, PO Box 1738, 3000 DR Rotterdam, the Netherlands (J.L.B., M.G.M.H.); Massachusetts General Hospital–Institute for Technology Assessment, Harvard Medical School, Boston, Mass (J.L.B.); and Harvard School of Public Health, Boston, Mass (M.G.M.H.). Received March 9, 2004; revision requested May 20; revision received July 6; accepted August 5. Address correspondence to M.G.M.H. (e-mail: m.hunink@erasmusmc.nl).
PURPOSE: To systematically review published data about the short- and long-term effects of exercise training and angioplasty on functional capacity and quality of life of patients with intermittent claudication.
MATERIALS AND METHODS: Articles published between January 1980 and February 2003 were included if patients had intermittent claudication treated with exercise training or angioplasty and if both functional capacity and quality-of-life scores from Medical Outcomes Study 36-Item Short Form health survey were reported for at least 3 months of follow-up. Data were pooled by using a random effects model and weighted means. Pooled results were compared between the treatment groups by using the 
2 test and the Student t test (
= .05, two sided).
RESULTS: In the analyses, five studies (202 patients) were included in the exercise group, and three studies (470 patients), in the angioplasty group. At 3 months of follow-up, the ankle-brachial index was significantly improved in the angioplasty group (mean change, 0.18; P < .01) but not in the exercise group (mean change, 0.01; P = .29). At 3 months, quality of life was significantly improved with regard to ratings of physical functioning and bodily pain in the exercise group (mean change, 18 and 10, respectively; P < .01) and physical role functioning in the angioplasty group (mean change, 30; P = .03). Mean change in ankle-brachial index significantly differed between the two treatment groups at 3 and 6 months (P < .01); mean change in quality-of-life scores did not.
CONCLUSION: Improvement in quality of life was demonstrated after both exercise training and angioplasty, whereas functional capacity showed significant improvement after angioplasty. The ankle-brachial index significantly differed between the two treatment groups at 3 and 6 months, whereas the quality-of-life scores did not.
© RSNA, 2005
This article has been cited by other articles:
|
|
 |
|
  J. G Regensteiner, W. R Hiatt, J. R Coll, M. H Criqui, D. Treat-Jacobson, M. M McDermott, and A. T Hirsch The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) Program Vascular Medicine, February 1, 2008; 13(1): 15 - 24. [Abstract] [PDF]
|
|
|
|
 |
|
 C. J. White and W. A. Gray Endovascular Therapies for Peripheral Arterial Disease: An Evidence-Based Review Circulation, November 6, 2007; 116(19): 2203 - 2215. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. J. R. van Beek and D. E. Malone Evidence-based Practice in Radiology Education: Why and How Should We Teach It? Radiology, June 1, 2007; 243(3): 633 - 640. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. White Intermittent Claudication N. Engl. J. Med., March 22, 2007; 356(12): 1241 - 1250. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| RADIOLOGY | RADIOGRAPHICS | RSNA JOURNALS ONLINE |
