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Spin-labeling Coronary MR Angiography with Steady-State Free Precession and Radial k-Space Sampling: Initial Results in Healthy Volunteers¹

¹ From the Department of Diagnostic Radiology, University Hospital, University of Technology (RWTH), Pauwelsstrasse 30, 52057 Aachen, Germany (M.K., A.B., R.W.G., E.S.); and the Department of Radiology, Division of MRI Research, Johns Hopkins University Medical School, Baltimore, Md (M.S.). Received May 13, 2004; revision requested July 29; revision received September 15; accepted October 20. Address correspondence to M.K. (e-mail: katoh{at}rad.rwth-aachen.de).

The purpose of this study was to prospectively compare free-breathing navigator-gated cardiac-triggered three-dimensional steady-state free precession (SSFP) spin-labeling coronary magnetic resonance (MR) angiography performed by using Cartesian k-space sampling with that performed by using radial k-space sampling. A new dedicated placement of the two-dimensional selective labeling pulse and an individually adjusted labeling delay time approved by the institutional review board were used. In 14 volunteers (eight men, six women; mean age, 28.8 years) who gave informed consent, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), vessel sharpness, vessel length, and subjective image quality were investigated. Differences between groups were analyzed with nonparametric tests (Wilcoxon, Pearson ²). Radial imaging, as compared with Cartesian imaging, resulted in a significant reduction in the severity of motion artifacts, as well as an increase in SNR (26.9 vs 12.0, P < .05) in the coronary arteries and CNR (23.1 vs 8.8, P < .05) between the coronary arteries and the myocardium. A tendency toward improved vessel sharpness and vessel length was also found with radial imaging. Radial SSFP imaging is a promising technique for spin-labeling coronary MR angiography.

© RSNA, 2005

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