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DOI: 10.1148/radiol.2381041602
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(Radiology 2006;238:16-39.)
© RSNA, 2006


Special Reviews

Evolving and Experimental Technologies in Medical Imaging1

Anthony B. Wolbarst, PhD and William R. Hendee, PhD

1 From the Department of Radiation Medicine, Georgetown University Medical School, Washington, DC (A.B.W.); and Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226 (W.R.H.). Received September 20, 2004; revision requested November 15; revision received December 9; accepted January 14, 2005; updated July 14; final version accepted August 5. Supported in part by grants from the National Institutes of Health (RO1 CA80490, P01 CA 87634) and GE Medical Systems. Address correspondence to W.R.H. (e-mail: whendee{at}mcw.edu).

Medical images are created by detecting radiation probes transmitted through or emitted or scattered by the body. The radiation, modulated through interactions with tissues, yields patterns that provide anatomic and/or physiologic information. X-rays, gamma rays, radiofrequency signals, and ultrasound waves are the standard probes, but others like visible and infrared light, microwaves, terahertz rays, and intrinsic and applied electric and magnetic fields are being explored. Some of the younger technologies, such as molecular imaging, may enhance existing imaging modalities; however, they also, in combination with nanotechnology, biotechnology, bioinformatics, and new forms of computational hardware and software, may well lead to novel approaches to clinical imaging. This review provides a brief overview of the current state of image-based diagnostic medicine and offers comments on the directions in which some of its subfields may be heading.

© RSNA, 2006




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