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Published online before print April 26, 2006, 10.1148/radiol.2393050228
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(Radiology 2006;239:856-862.)
© RSNA, 2006

Technical Developments

Cine Delayed-Enhancement MR Imaging of the Heart: Initial Experience1

Randolph M. Setser, DSc, Jae K. Kim, MD, PhD, Yiu Cho Chung, PhD, Kevin Chen, MD, Arthur E. Stillman, MD, PhD, Ralf Loeffler, PhD, Orlando P. Simonetti, PhD, Joan A. Weaver, RT, Michael L. Lieber, MS and Richard D. White, MD

1 From the Section of Cardiovascular Imaging, Division of Radiology (R.M.S., J.K.K., K.C., A.E.S., J.A.W., R.D.W.), and Department of Biostatistics and Epidemiology (M.L.L.), the Cleveland Clinic Foundation, 9500 Euclid Ave, Desk HB6, Cleveland, OH 44195; Siemens Medical Solutions, Chicago, Ill (Y.C.C., O.P.S.); and Siemens Medical Solutions, Erlangen, Germany (R.L.). Received February 11, 2005; revision requested April 11; revision received June 30; accepted July 21; final version accepted September 1. Address correspondence to R.M.S. (e-mail: setserr{at}ccf.org).

This study was performed by using an institutional review board–approved protocol, with waived informed consent and HIPAA compliance. The purpose of this study was to preliminarily evaluate a cine delayed-enhancement (DE) pulse sequence for depiction of wall motion and myocardial scar extent during a single acquisition. The technique is based on inversion-recovery single-shot balanced steady-state free precession magnetic resonance imaging. Cine DE images were acquired in 26 patients (18 men, eight women; age range, 25–84 years; mean age, 61 years ± 13 [standard deviation]). Image contrast was consistent throughout each series. Overall (ie, with both readers' scores averaged), the cine DE imaging–depicted wall motion was scored correctly in 71% of myocardial segments. Scar extent was scored correctly in 76% of segments; in no patient was scarring missed. Cine DE imaging is a promising technique for simultaneous visualization of wall motion and myocardial scar extent.

© RSNA, 2006