Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Published online before print August 23, 2006, 10.1148/radiol.2411050987
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Appendix
Right arrow All Versions of this Article:
2411050987v1
241/1/243    most recent
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bricault, I.
Right arrow Articles by Silverman, S. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bricault, I.
Right arrow Articles by Silverman, S. G.
(Radiology 2006;241:243-250.)
© RSNA, 2006

Technical Developments

Liver Metastases: 3D Shape–based Analysis of CT Scans for Detection of Local Recurrence after Radiofrequency Ablation1

Ivan Bricault, MD, PhD, Ron Kikinis, MD, Paul R. Morrison, MS, Eric vanSonnenberg, MD, Kemal Tuncali, MD and Stuart G. Silverman, MD

1 From the Department of Radiology, University Hospital Michallon, BP 217, 38043 Grenoble, France (I.B.); TIMC-IMAG-CNRS Laboratory, Grenoble, France (I.B.); and Department of Radiology, Brigham and Women's Hospital, Boston, Mass (R.K., P.R.M., E.v.S., K.T., S.G.S.). Received June 13, 2005; revision requested August 3; revision received November 1; accepted November 23; final version accepted December 22. Supported in part by a study grant from the French Radiological Society. Address correspondence to I.B. (e-mail: Ivan.Bricault{at}imag.fr).

This HIPAA-compliant pilot study had internal review board approval; informed consent was waived. The purpose was to determine retrospectively the diagnostic performance of a computer-aided three-dimensional (3D) analytic tool for assessing local recurrences of liver metastases by quantifying shape changes in ablated tumors on computed tomographic (CT) scans for follow-up of radiofrequency (RF) ablation. Positron emission tomographic and long-term CT follow-up images were reference standards. Fifty-six follow-up CT scans of 12 liver metastases (mean size, 4.0 cm) in nine patients treated with RF ablation were retrospectively analyzed. After the 1st month following RF ablation, the 3D analytic tool helped quantify ablated tumor shape variations and revealed recurrences even in the absence of abnormal enhancement (sensitivity, seven of seven; specificity, three of five). The 3D tool would have revealed a recurrence before it was reported clinically in two patients. Although results are preliminary, a 3D analytic tool based on shape may be useful in assessing RF ablation results.

Supplemental material: http://radiology.rsnajnls.org/cgi/content/full/2411050987/DC1

© RSNA, 2006






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 2006 by the Radiological Society of North America.