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DOI: 10.1148/radiol.2431060310
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(Radiology 2007;243:220-228.)
© RSNA, 2007

Technical Developments

Three-dimensional Black-Blood MR Imaging of Carotid Arteries with Segmented Steady-State Free Precession: Initial Experience1

Ioannis Koktzoglou, PhD, Yiu-Cho Chung, PhD, Timothy J. Carroll, PhD, Orlando P. Simonetti, PhD, Mark D. Morasch, MD and Debiao Li, PhD

1 From the Department of Radiology (I.K., T.J.C., D.L.) and Division of Vascular Surgery, Department of Surgery (M.D.M.), Northwestern University, 448 E Ontario St, Suite 700, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (I.K., T.J.C., D.L.); Siemens Medical Solutions, Chicago, Ill (Y.C.C.); and Department of Cardiovascular Medicine and Radiology, College of Medicine and Public Health, the Ohio State University, Columbus, Ohio (O.P.S.). Received February 17, 2006; revision requested April 21; revision received June 5; final version accepted August 1. I.K. supported by the Dr John N. Nicholson Fellowship. Address correspondence to I.K. (e-mail: ioannis.koktzoglou{at}gmail.com).

This HIPAA-compliant study had institutional review board approval. Informed consent was obtained. The purpose was to prospectively evaluate a segmented three-dimensional (3D) double inversion recovery (DIR)–prepared steady-state free precession (SSFP) magnetic resonance (MR) imaging sequence for fast high-spatial-resolution black-blood carotid arterial wall imaging. Carotid wall–lumen contrast-to-noise ratio (CNR) obtained with this sequence was compared with those obtained with two-dimensional (2D) single- and multisection black-blood fast spin-echo (SE) sequences. MR imaging of both carotid artery bifurcations over 3 cm of transverse coverage was performed in eight volunteers (seven men, one woman; age range, 26–56 years) with no known history of carotid artery disease. Adjusted for section thickness and imaging time per section, higher effective mean CNR was achieved with segmented 3D DIR-prepared SSFP than with single-section 2D DIR-prepared fast SE or multisection 2D saturation-band fast SE (P < .05). Segmented 3D DIR-prepared SSFP enables black-blood carotid arterial wall MR imaging with contiguous thin-section coverage and greater imaging speed and effective CNR than conventional 2D fast SE techniques.

© RSNA, 2007




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