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1 From the Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (M.H.B., A.A.Z., R.R., K.H.Z., R.K., A.M.N., U.J.S.); Department of Surgery/Orthopedic Surgery, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany (M.H.B., F.F.H.); Department of Health Care Policy, Harvard Medical School, Boston, Mass (K.H.Z.); Department of Radiology, Medical University of South Carolina, 169 Ashley Ave, Charleston, SC 29425 (Z.R., U.J.S.); and Department of Radiology, Boston University School of Medicine, Boston, Mass (A.M.N.). From the 2004 RSNA Annual Meeting. Received February 7, 2005; revision requested April 19; revision received July 6, 2006; accepted August 22; final version accepted October 27. U.J.S. is a consultant to and receives research support from Siemens Medical Solutions. Address correspondence to U.J.S. (e-mail: schoepf{at}musc.edu).
The aim of the study was to retrospectively determine the potential for radiation dose reduction at multidetector computed tomography (CT) of the paranasal sinus by using computer simulation of the effect of lowradiation dose acquisition on diagnostic image quality. This HIPAA compliant study was approved by the institutional human research committee. The need for informed patient consent was waived. Twenty patients underwent four-section CT at 120 kV, 170 mAs, and 4 x 1-mm collimation. Artificial image noise was added to the CT raw data by using a dedicated software platform. Acquisitions with effective tube currents of 134, 100, 67, and 33 mAs were simulated. Each raw data set was reconstructed with bone and soft-tissue algorithms, and two radiologists independently rated the images in blinded fashion. A two-sided paired Student t test was used for statistical analysis. The lowest radiation dose that still provided diagnostic quality was
67 effective mAs for osseous structures and
134 effective mAs for the optic nerve and the inferior rectus muscle. On the basis of the results, tube currents can be lowered and radiation dose reduced by 20%.
© RSNA, 2007
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