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Published online before print April 19, 2007, 10.1148/radiol.2433060819
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(Radiology 2007;243:853-861.)
© RSNA, 2007


Technical Developments

High-Spatial-Resolution Contrast-enhanced MR Angiography of the Intracranial Venous System with Fourfold Accelerated Two-dimensional Sensitivity Encoding1

Houchun H. Hu, PhD, Norbert G. Campeau, MD, John Huston, III, MD, David G. Kruger, PhD, Clifton R. Haider, BS, and Stephen J. Riederer, PhD

1 From the Magnetic Resonance Laboratory, Department of Radiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905. Received May 10, 2006; revision requested July 11; revision received August 24; final version accepted October 5. Supported by National Institutes of Health grant EB000212. Address correspondence to S.J.R. (e-mail: riederer{at}mayo.edu).

Informed consent was obtained; the study was HIPAA compliant and institutional review board approved. Fourfold accelerated (FFA) two-dimensional (2D) sensitivity encoding (SENSE) (65 seconds) was prospectively compared with its nonaccelerated counterpart (4 minutes 20 seconds) for diagnostic image quality and sharpness of visualization of blood vessels at 1.5 T with three-dimensional (3D) intracranial contrast-enhanced magnetic resonance venography in 18 consecutive volunteers (10 men, eight women; mean age, 48.4 years) and two patients (55-year-old man, 30-year-old woman). Two readers compared FFA 2D SENSE results with results from its nonaccelerated counterpart; they rated visualization of large and medium sinuses as equivalent (P > .1) and that of small deep cerebral veins (P < .01) and superficial cerebral veins (P < .001) as superior. Overall diagnostic image quality ratings were excellent for 62% and 80% of nonaccelerated and FFA 2D SENSE results, respectively (P < .05). FFA 2D SENSE may become the method of choice for fast visualization of intracranial venous vasculature in clinical practice.

© RSNA, 2007




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