| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Innovations |
1 From the Laboratory for Preclinical Imaging and Imaging Technology, Clinic of Radiology, University of Tübingen, Röntgenweg 13, 72076 Tübingen, Germany (M.S.J., C.D.C., B.J.P.); Department of Biomedical Engineering, University of California, Davis, Calif (C.C., S.R.C.); Siemens Preclinical Solutions, Knoxville, Tenn (B.K.S., S.B.S., R.E.N.); and Bruker BioSpin MRI, Ettlingen, Germany (W.I.J.). Received October 10, 2006; revision requested December 7; revision received December 20; accepted January 23, 2007; final version accepted March 1. Supported by NIH grant EB004483-01. Address corres-pondence to B.J.P. (e-mail: bernd.pichler{at}med.uni-tuebingen.de).
Purpose: To prospectively use compact avalanche photodiodes instead of photomultiplier tubes to integrate a positron emission tomographic (PET) detector and a 7-T magnetic resonance (MR) imager.
Materials and Methods: All animal experiments were performed in accordance with the University of Tübingen guidelines and the German law for the protection of animals. A compact lutetium oxyorthosilicate–avalanche photodiode PET detector was built and optimized to operate within a 7-T MR imager. The detector performance was investigated both outside and inside the magnet, and MR image quality was evaluated with and without the PET detector. Two PET detectors were set up opposite each other and operated in coincidence to acquire PET images in the step-and-shoot mode in a mouse head specimen after injection of fluorine 18 fluorodeoxyglucose.
Results: The performance of the PET detector when operated inside the magnet during MR image acquisition showed little degradation in energy resolution (increase from 14.6% to 15.9%). The PET detector did not influence MR imaging. The fused PET and MR images showed an anatomic match and no degradation of image quality.
Conclusion: Simultaneous PET and MR imaging with a 7-T system was deemed feasible.
© RSNA, 2007
Related Article
Radiology 2007 244: 639-642.
This article has been cited by other articles:
|
|
 |
|
  A. Martinez-Moller, M. Souvatzoglou, G. Delso, R. A. Bundschuh, C. Chefd'hotel, S. I. Ziegler, N. Navab, M. Schwaiger, and S. G. Nekolla Tissue Classification as a Potential Approach for Attenuation Correction in Whole-Body PET/MRI: Evaluation with PET/CT Data J. Nucl. Med., April 1, 2009; 50(4): 520 - 526. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Morikawa, Y. Demura, T. Ishizaki, S. Ameshima, I. Miyamori, M. Sasaki, T. Tsuchida, H. Kimura, Y. Fujibayashi, and H. Okazawa The Effectiveness of 18F-FDG PET/CT Combined with STIR MRI for Diagnosing Nodal Involvement in the Thorax J. Nucl. Med., January 1, 2009; 50(1): 81 - 87. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hofmann, F. Steinke, V. Scheel, G. Charpiat, J. Farquhar, P. Aschoff, M. Brady, B. Scholkopf, and B. J. Pichler MRI-Based Attenuation Correction for PET/MRI: A Novel Approach Combining Pattern Recognition and Atlas Registration J. Nucl. Med., November 1, 2008; 49(11): 1875 - 1883. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-P. W. Schlemmer, B. J. Pichler, M. Schmand, Z. Burbar, C. Michel, R. Ladebeck, K. Jattke, D. Townsend, C. Nahmias, P. K. Jacob, et al. Simultaneous MR/PET Imaging of the Human Brain: Feasibility Study Radiology, September 1, 2008; 248(3): 1028 - 1035. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. J. Pichler, H. F. Wehrl, and M. S. Judenhofer Latest Advances in Molecular Imaging Instrumentation J. Nucl. Med., June 1, 2008; 49(Suppl_2): 5S - 23S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Catana, D. Procissi, Y. Wu, M. S. Judenhofer, J. Qi, B. J. Pichler, R. E. Jacobs, and S. R. Cherry Simultaneous in vivo positron emission tomography and magnetic resonance imaging PNAS, March 11, 2008; 105(10): 3705 - 3710. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Zaidi Is MR-guided Attenuation Correction a Viable Option for Dual-Modality PET/MR Imaging? Radiology, September 1, 2007; 244(3): 639 - 642. [Full Text] [PDF]
|
|
