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Recent Myocardial Infarction: Assessment with Unenhanced T1-weighted MR Imaging¹

¹ From the Department of Research and Education, DeMatteis MRI, St Francis Hospital, 100 Port Washington Blvd, Roslyn, NY 11576 (J.W.G., S.A., J.H.); and Program in Biomedical Engineering, SUNY Stony Brook, Stony Brook, NY (J.W.G.). Received September 13, 2006; revision requested November 9; revision received December 5; accepted January 15, 2007; final version accepted March 7. Supported by a grant from the American Heart Association (0635029N). Address correspondence to J.W.G. (e-mail: James.Goldfarb{at}chsli.org).

The purpose of the study was to prospectively evaluate a T1-weighted technique for detection of myocardial edema resulting from recent myocardial infarction (MI) or intervention. This study was HIPAA compliant and institutional review board approved. Fifteen men and one woman (mean age, 57.8 years ± 11.5 [standard deviation]) were examined with T1-weighted magnetic resonance (MR) imaging and inversion-recovery cine pulse sequence in two groups, recent MI and chronic MI, and gave informed consent. T1 relaxation times of MI and adjacent myocardium were compared (Student t test and correlation analysis). In patients with recent MI, areas of myocardial edema were well depicted with T1-weighted MR imaging. T1 relaxation times of recent infarcts were longer than those of older MIs (925 msec ± 169 vs 551 msec ± 107, P < .001). From local edema, T1 relaxation time of infarcted myocardium is increased, may remain elevated for 2 months, and enables imaging with T1-weighted techniques.

© RSNA, 2007