Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Published online before print September 21, 2007, 10.1148/radiol.2452060906
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
2452060906v1
245/2/556    most recent
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cash, C. J. C.
Right arrow Articles by Prager, R. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cash, C. J. C.
Right arrow Articles by Prager, R. W.
(Radiology 2007;245:556-566.)
© RSNA, 2007

Technical Developments

Breast Cancers: Noninvasive Method of Preoperative Localization with Three-dimensional US and Surface Contour Mapping1

Charlotte J. C. Cash, MRCP, FRCR, Charlotte E. Coles, MRCP, FRCR, Graham M. Treece, MA, PhD, Anand D. Purushotham, MD, FRCS, Peter Britton, FRCS, FRCR, Ruchi Sinnatamby, MRCP, FRCR, Andrew H. Gee, MA, PhD, and Richard W. Prager, MA, PhD

1 From the Departments of Radiology (C.J.C.C.), Oncology (C.E.C.), Surgery (A.D.P.), and Engineering (G.M.T., A.H.G., R.W.P.), Cambridge University, Hills Road, Cambridge CB22QQ, England; and Department of Radiology, Addenbrooke's Hospital NHS Trust, Cambridge, England (P.B., R.S.). Received May 24, 2006; revision requested July 27; revision received October 20; accepted November 21; final version accepted April 2, 2007. Address correspondence to C.J.C.C. (e-mail: cjcc2{at}ukonline.co.uk).

Formal ethical approval was granted by the local research ethics committee; all participants gave written consent. The purpose of the study was to prospectively evaluate the feasibility of a noninvasive method of breast tumor localization in 25 participants, based on the coregistration of three-dimensional (3D) ultrasonographic (US) data with surface contour data obtained by using a 3D laser camera. The tumor is segmented from the US data, and a surface-rendered 3D image of the tumor, in relation to the breast surface contour, is produced. From a personal computer in the operating room, the surgeon can dynamically view a 3D image of the tumor within the breast. This noninvasive method was equivalent to conventional techniques in 18 of 25 patients but was less successful in larger-breasted patients. In selected patients, this localization method could provide an alternative to conventional invasive techniques and can offer both spatial localization and tumor morphology.

© RSNA, 2007