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Determination of Peak Velocity in Stenotic Areas: Echocardiography versus k-t SENSE Accelerated MR Fourier Velocity Encoding¹

¹ From the Institute for Biomedical Engineering, University and Swiss Federal Institute of Technology Zurich, Wolfgang-Pauli-Str 10, CH-8093 Zurich, Switzerland (C.B., S.K., P.B.); Division of Imaging Sciences, Guy's Hospital, King's College, London, England (M.S.H., R.R.); Novartis Institutes for BioMedical Research, Cambridge, Mass (J.T.); and MR-Centre, Aarhus University Hospital, Skejby, Aarhus, Denmark (E.M.P.). Received August 7, 2006; revision requested October 13; revision received December 22; accepted January 23, 2007; final version accepted April 2. Supported by the Strategic Excellence Project Life Sciences (grant TH7/02-2) of the Swiss Federal Institute of Technology Zurich, the Danish Heart Foundation (grant #02-2-3-43-22021), and Philips Medical Systems, Best, the Netherlands. Address correspondence to C.B. (e-mail: baltes{at}biomed.ee.ethz.ch).

The study was approved by the local ethical committees, and informed consent from each participant was obtained. The purpose of the study was to compare accelerated magnetic resonance (MR) Fourier velocity encoding (FVE), MR phase-contrast velocity mapping, and echocardiography with respect to peak velocity determination in vascular or valvular stenoses. FVE data collection was accelerated by using the k-space and time sensitivity encoding, or k-t SENSE, technique. Peak velocities were evaluated in five healthy volunteers (one woman, four men; mean age, 28 years; range, 23–34 years), three patients with stenotic aortic valves (two women, one man; mean age, 67 years; range, 39–82 years), two patients with pulmonary valvular stenosis (a 14-year-old girl and a 36-year-old man), and two patients with aortic stenosis (two women aged 18 and 27 years). In volunteers, peak velocity determined by the different methods agreed well. In patients, similar peak velocities were obtained by using accelerated MR FVE and echocardiography, while phase-contrast MR imaging results tended to underestimate these values.

© RSNA, 2007