Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Published online before print December 4, 2007, 10.1148/radiol.2462070198

(Radiology 2007;246:394.)

A more recent version of this article appeared on December 1, 2007
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow All Versions of this Article:
2462070198v1
246/2/394    most recent
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Grotenhuis, H. B.
Right arrow Articles by Kroft, L. J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Grotenhuis, H. B.
Right arrow Articles by Kroft, L. J. M.
© RSNA, 2007

Cardiac Imaging

MR Imaging of Right Ventricular Function after the Ross Procedure for Aortic Valve Replacement: Initial Experience1

Heynric B. Grotenhuis, MD, Albert de Roos, MD, PhD, Jaap Ottenkamp, MD, PhD, Paul H. Schoof, MD, PhD, Hubert W. Vliegen, MD, PhD, and Lucia J. M. Kroft, MD, PhD

1 From the Department of Radiology (H.B.G., A.d.R., L.J.M.K.), Department of Pediatric Cardiology, Center for Congenital Anomalies of the Heart (H.B.G., J.O.), Department of Cardiothoracic Surgery (P.H.S.), and Department of Cardiology (H.W.V.), Leiden University Medical Center, Albinusdreef 2, C2-S, 2300 RC Leiden, the Netherlands. Received January 30, 2007; revision requested April 3; revision received April 17; accepted May 7; final version accepted July 10. Address correspondence to L.J.M.K. (e-mail: L.J.M.Kroft{at}lumc.nl).

Purpose: To prospectively assess right ventricular (RV) function after the Ross procedure by using magnetic resonance (MR) imaging.

Materials and Methods: The local ethics committee approved the study and informed consent was obtained from all participants prior to enrollment in the study. Seventeen patients (15 male, two female; mean age ± standard deviation, 19 years ± 3.9; imaging performed 8.3 years after surgery ± 3.2) and 17 matched controls (15 male, two female; mean age ± standard deviation, 20 years ± 3.9) were studied by using MR imaging. Standard velocity-encoded and multisection multiphase imaging sequences were used to assess homograft valve function, systolic and diastolic RV function, and RV mass. The two-tailed Mann-Whitney U test and the Spearman rank correlation coefficient were used for statistical analysis.

Results: Minor degrees of homograft stenosis (peak flow velocity between 1.5 and 3.0 m/sec across the homograft valve) were found in 12 of 17 patients but not in controls (P < .001). A larger RV mass was present in Ross patients than in controls (17.0 g/m2 ± 4.8 vs 10.9 g/m2 ± 5.6, P = .004). In addition, impaired diastolic RV function was found, as shown by a decreased mean tricuspid valve early filling phase–atrial contraction phase (E/A) peak flow velocity ratio (1.56 ± 0.75 vs 2.05 ± 0.58, P = .03). Peak flow velocity across the homograft valve correlated with RV mass (r = 0.38, P = .03) and tricuspid valve E/A peak flow velocity ratio (r = 0.39, P = .02). RV systolic function was normal in Ross patients (mean RV ejection fraction, 52% ± 8 vs 51% ± 5; P = .74).

Conclusion: RV hypertrophy and RV diastolic dysfunction are frequently observed in patients after the Ross procedure, even in the absence of overt homograft stenosis. RV systolic function is still preserved.

© RSNA, 2007