Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Published online before print August 18, 2008, 10.1148/radiol.2483072003

(Radiology 2008;249:301.)

A more recent version of this article appeared on October 1, 2008
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow All Versions of this Article:
2483072003v1
249/1/301    most recent
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sarwar, A.
Right arrow Articles by Hoffmann, U.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sarwar, A.
Right arrow Articles by Hoffmann, U.
© RSNA, 2008

Technical Developments

Calcified Plaque: Measurement of Area at Thin-Section Flat-Panel CT and 64-Section Multidetector CT and Comparison with Histopathologic Findings1

Ammar Sarwar, MD, Johannes Rieber, MD, Eline A. Q. Mooyaart, MS, Sujith K. Seneviratne, MBBS, Stuart L. Houser, MD, Fabian Bamberg, MD, O. Christopher Raffel, MD, Rajiv Gupta, PhD, MD, Mannudeep K. Kalra, MD, Homer Pien, PhD, Hang Lee, PhD, Thomas J. Brady, MD, and Udo Hoffmann, MD, MPH

1 From the Cardiac MR PET CT Program, Massachusetts General Hospital, 165 Cambridge St, 4th Floor, Suite 400, Boston, MA 02114. Received November 19, 2007; revision requested January 16, 2008; final revision received February 19; accepted March 5; final version accepted March 19. Address correspondence to U.H. (e-mail: uhoffmann{at}partners.org).

The purpose of this study was to assess the blooming artifacts in ex vivo coronary arteries at multidetector computed tomography (CT) and flat-panel–volume CT by comparing measured areas of calcified plaque with respect to the reference standard of histopathologic findings. Three ex vivo hearts were scanned with multidetector CT and flat-panel–volume CT after institutional review board approval. The area of calcified plaque was measured at histopathologic examination, multidetector CT, and flat-panel–volume CT. The plaque area was overestimated at multidetector CT by 400% (4.61/1.15) on average, and the predicted difference between the measurements was significant (3.46 mm2, P = .018). The average overestimation of plaque area at flat-panel–volume CT was twofold (214% [2.18/1.02]), and the predicted difference was smaller (1.16 mm2, P = .08). The extent of the blooming artifact in visualizing calcified coronary plaque is reduced by using flat-panel–volume CT.

© RSNA, 2008




This article has been cited by other articles:


Home page
 JAMAHome page
R. Met, S. Bipat, D. A. Legemate, J. A. Reekers, and M. J. W. Koelemay
Diagnostic Performance of Computed Tomography Angiography in Peripheral Arterial Disease: A Systematic Review and Meta-analysis
JAMA, January 28, 2009; 301(4): 415 - 424.
[Abstract] [Full Text] [PDF]