Published online before print October 10, 2008, 10.1148/radiol.2492080560
(Radiology 2008;249:1010-1016.)
© RSNA, 2008
Multienergy Photon-counting K-edge Imaging: Potential for Improved Luminal Depiction in Vascular Imaging1
Sebastian Feuerlein, MD,
Ewald Roessl, PhD,
Roland Proksa, PhD,
Gerhard Martens, PhD,
Oliver Klass, MD,
Martin Jeltsch, MD,
Volker Rasche, PhD,
Hans-Juergen Brambs, MD,
Martin H. K. Hoffmann, MD, and
Jens-Peter Schlomka, PhD
1 From the Department of Diagnostic and Interventional Radiology (S.F., O.K., M.J., H.J.B., M.H.K.H.) and Department of Cardiology (V.R.), University of Ulm, Steinhoevelstrasse 9, 89075 Ulm, Germany; and Philips Research Europe, Sector Medical Imaging Systems, Hamburg, Germany (E.R., R.P., G.M., J.P.S.). Received March 26, 2008; revision requested May 16; revision received May 28; accepted June 5; final version accepted June 11.
Address correspondence to S.F. (e-mail: sfeuerlein{at}yahoo.com).
The purpose of this study was to investigate whether spectral computed tomography (CT) has the potential to improve luminal depiction by differentiating among intravascular gadolinium-based contrast agent, calcified plaque, and stent material by using the characteristic k edge of gadolinium. A preclinical spectral CT scanner with a photon-counting detector and six energy threshold levels was used to scan a phantom vessel. A partially occluded stent was simulated by using a calcified plaque isoattenuated to a surrounding gadolinium chelate solution. The reconstructed images showed an effective isolation of the gadolinium with subsequent clear depiction of the perfused vessel lumen. The calcified plaque and the stent material are suppressed.
© RSNA, 2008
Copyright © 2008 by the Radiological Society of North America.