Local Tumor Recurrence following Breast-Conservation Therapy: Correlation of Histopathologic Findings with Detection Method and Mammographic Findings1
Catherine S. Giess, MD,
Delia M. Keating, MD,
Michael P. Osborne, MD and
Ruth Rosenblatt, MD
1 From the Departments of Radiology (C.S.G., D.M.K., R.R.) and Surgery (M.P.O.), New York Presbyterian Hospital–Weill Medical College of Cornell University, Strang Cornell Breast Center, New York. Received June 17, 1998; revision requested August 6; final revision received November 17; accepted March 26, 1999. Address reprint requests to C.S.G., Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021.
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Figure 1a. (a) Collimated right craniocaudal mammogram obtained during a needle localization in a 52-year-old woman shows the localization needle as it extends through a cluster of pleomorphic microcalcifications (arrowhead). Histopathologic analysis yielded mixed comedo and noncomedo DCIS. (b) Collimated right craniocaudal mammogram obtained 25 months after breast-conservation therapy demonstrates new pleomorphic microcalcifications (arrowheads) in a linear distribution adjacent to the lumpectomy bed (arrow). Histopathologic analysis yielded cribriform-type DCIS with necrosis.
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Figure 1b. (a) Collimated right craniocaudal mammogram obtained during a needle localization in a 52-year-old woman shows the localization needle as it extends through a cluster of pleomorphic microcalcifications (arrowhead). Histopathologic analysis yielded mixed comedo and noncomedo DCIS. (b) Collimated right craniocaudal mammogram obtained 25 months after breast-conservation therapy demonstrates new pleomorphic microcalcifications (arrowheads) in a linear distribution adjacent to the lumpectomy bed (arrow). Histopathologic analysis yielded cribriform-type DCIS with necrosis.
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Figure 2a. (a) Collimated left craniocaudal mammogram obtained in a 59-year-old woman shows an ill-defined mass (arrowhead). Histopathologic analysis yielded poorly differentiated invasive ductal carcinoma. (b) Collimated left craniocaudal mammogram obtained 34 months after breast-conservation therapy shows an ill-defined mass (arrowhead) anterior to the lumpectomy bed, which is marked by surgical clips. Histopathologic analysis yielded recurrent poorly differentiated invasive ductal carcinoma.
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Figure 2b. (a) Collimated left craniocaudal mammogram obtained in a 59-year-old woman shows an ill-defined mass (arrowhead). Histopathologic analysis yielded poorly differentiated invasive ductal carcinoma. (b) Collimated left craniocaudal mammogram obtained 34 months after breast-conservation therapy shows an ill-defined mass (arrowhead) anterior to the lumpectomy bed, which is marked by surgical clips. Histopathologic analysis yielded recurrent poorly differentiated invasive ductal carcinoma.
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Figure 3a. (a) Left mediolateral oblique mammogram obtained in a 54-year-old woman demonstrates an ill-defined mass (arrow). Histopathologic analysis yielded invasive ductal carcinoma, with prominent mucin production. A metallic wire identifies the site of a previous biopsy of a benign lesion. (b) Collimated mediolateral oblique magnification mammogram obtained 20 months after breast-conservation therapy demonstrates numerous linear and pleomorphic microcalcifications (arrows) immediately anterior to the lumpectomy bed. Histopathologic analysis yielded recurrent invasive ductal carcinoma with comedo-type DCIS. A metallic wire identifies the cutaneous lumpectomy scar.
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Figure 3b. (a) Left mediolateral oblique mammogram obtained in a 54-year-old woman demonstrates an ill-defined mass (arrow). Histopathologic analysis yielded invasive ductal carcinoma, with prominent mucin production. A metallic wire identifies the site of a previous biopsy of a benign lesion. (b) Collimated mediolateral oblique magnification mammogram obtained 20 months after breast-conservation therapy demonstrates numerous linear and pleomorphic microcalcifications (arrows) immediately anterior to the lumpectomy bed. Histopathologic analysis yielded recurrent invasive ductal carcinoma with comedo-type DCIS. A metallic wire identifies the cutaneous lumpectomy scar.
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Copyright © 1999 by the Radiological Society of North America.
