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Stereotactic Core-Needle Breast Biopsy: A Multi-institutional Prospective Trial1

R. James Brenner, MD, Lawrence W. Bassett, MD, Laurie L. Fajardo, MD, D. David Dershaw, MD, W. Phil Evans, III, MD, Rebecca Hunt, MD, Carol Lee, MD, Irena Tocino, MD, Paul Fisher, MD, Marie McCombs, MD, Valerie P. Jackson, MD, Stephen A. Feig, MD, Ellen B. Mendelson, MD, Frederick R. Margolin, MD, Richard Bird, BA and James Sayre, PhD

1 From the Joyce Eisenberg Keefer Breast Center, John Wayne Cancer Institute, St Johns Health Center, 1328 22nd St, Santa Monica, CA 90404 (R.J.B.). Affiliations for all other authors are listed at the end of this article. Received January 26, 2000; revision requested March 3; final revision received July 19; accepted August 28. Address correspondence to R.J.B. (e-mail: James.Brenner@stjohns.org).



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  		Figure 1. Triage of patients. Flow diagram indicates disposition of 1,003 patients undergoing CNB. During median follow-up (F/U) of 24 months, six interval cancers were diagnosed.

 


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  		Figure 2. Receiver operating characteristic curve analysis (30,31) of the effects of strict, working, and applied sensitivities. The area under the curve is 0.974 ± 0.017.

 




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