DOI: 10.1148/radiol.2203001545
Benign and Malignant Breast Masses and Axillary Nodes: Evaluation with Echo-enhanced Color Power Doppler US1
Wei Tse Yang, FRCR,
Constantine Metreweli, FRCR, FRCP,
Peggo K. W. Lam, MPhil and
Jenny Chang, MD, MRCP
1 From the Department of Diagnostic Radiology and Organ Imaging (W.T.Y., C.M.) and the Center for Clinical Trials and Epidemiological Research (P.K.W.L.), Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong; and the Breast Care Center, Baylor College of Medicine, Houston, Tex (J.C.). Received September 18, 2000; revision requested November 2; final revision received March 15, 2001; accepted March 19. Supported in part by the University Grants Council Direct Grant for Research, Chinese University of Hong Kong, project code 2040753 and a research grant from Schering, Berlin, Germany. Address correspondence to W.T.Y. (e-mail: weitsetan@cuhk.edu.hk).
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Figure 1a. (a) Precontrast radial color power Doppler US image of a primary breast cancer shows central (open arrows) and peripheral (solid arrows) vessels. (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows an increase in central (open arrows), peripheral (solid arrow), and side-branching (arrowheads) vessels.
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Figure 1b. (a) Precontrast radial color power Doppler US image of a primary breast cancer shows central (open arrows) and peripheral (solid arrows) vessels. (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows an increase in central (open arrows), peripheral (solid arrow), and side-branching (arrowheads) vessels.
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Figure 2a. (a) Precontrast antiradial color power Doppler US image of a benign fibroadenoma shows sparse peripheral vessels (arrows). (b) Postcontrast antiradial color power Doppler US image of the same lesion as in a shows an increase in peripheral (long arrows) and central (short arrow) vessels.
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Figure 2b. (a) Precontrast antiradial color power Doppler US image of a benign fibroadenoma shows sparse peripheral vessels (arrows). (b) Postcontrast antiradial color power Doppler US image of the same lesion as in a shows an increase in peripheral (long arrows) and central (short arrow) vessels.
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Figure 3a. (a) Precontrast radial color power Doppler US image of a benign axillary node shows a single central perhilar vessel (arrow). (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows an increase in central perhilar (long thin arrows), central (short arrow), and peripheral (long thick arrows) vessels.
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Figure 3b. (a) Precontrast radial color power Doppler US image of a benign axillary node shows a single central perhilar vessel (arrow). (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows an increase in central perhilar (long thin arrows), central (short arrow), and peripheral (long thick arrows) vessels.
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Figure 4a. (a) Precontrast radial color power Doppler US image of a malignant axillary node shows central (open arrow) and peripheral (solid arrow) vessels. (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows a florid increase in central (arrows) and peripheral (arrowheads) vessels. (c) Precontrast radial color power Doppler US of the corresponding breast cancer in the same patient as in a shows a solitary tiny vessel (arrow) outside of the lesion. (d) Postcontrast radial color power Doppler US image of the same lesion as in c shows a moderate increase in the number of peripheral vessels (arrows). This increase is markedly lower than the increase in peripheral vessel number in the axillary node seen in b.
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Figure 4b. (a) Precontrast radial color power Doppler US image of a malignant axillary node shows central (open arrow) and peripheral (solid arrow) vessels. (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows a florid increase in central (arrows) and peripheral (arrowheads) vessels. (c) Precontrast radial color power Doppler US of the corresponding breast cancer in the same patient as in a shows a solitary tiny vessel (arrow) outside of the lesion. (d) Postcontrast radial color power Doppler US image of the same lesion as in c shows a moderate increase in the number of peripheral vessels (arrows). This increase is markedly lower than the increase in peripheral vessel number in the axillary node seen in b.
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Figure 4c. (a) Precontrast radial color power Doppler US image of a malignant axillary node shows central (open arrow) and peripheral (solid arrow) vessels. (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows a florid increase in central (arrows) and peripheral (arrowheads) vessels. (c) Precontrast radial color power Doppler US of the corresponding breast cancer in the same patient as in a shows a solitary tiny vessel (arrow) outside of the lesion. (d) Postcontrast radial color power Doppler US image of the same lesion as in c shows a moderate increase in the number of peripheral vessels (arrows). This increase is markedly lower than the increase in peripheral vessel number in the axillary node seen in b.
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Figure 4d. (a) Precontrast radial color power Doppler US image of a malignant axillary node shows central (open arrow) and peripheral (solid arrow) vessels. (b) Postcontrast radial color power Doppler US image of the same lesion as in a shows a florid increase in central (arrows) and peripheral (arrowheads) vessels. (c) Precontrast radial color power Doppler US of the corresponding breast cancer in the same patient as in a shows a solitary tiny vessel (arrow) outside of the lesion. (d) Postcontrast radial color power Doppler US image of the same lesion as in c shows a moderate increase in the number of peripheral vessels (arrows). This increase is markedly lower than the increase in peripheral vessel number in the axillary node seen in b.
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Figure 5a. (a) Graph illustrates results of receiver operating characteristic analysis of the postcontrast peripheral vessel numbers in 86 breast masses, for classification of benign and malignant disease. The area under the curve is 0.77, and the optimal cutoff value is four postcontrast peripheral vessels. (b) Graph illustrates results of receiver operating characteristic analysis of the combined score for increase in peripheral vessel number and duration of enhancement in 32 axillary lymph nodes, for classification of benign and malignant disease. The area under the curve is 0.86, and the optimal score is 0.41.
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Figure 5b. (a) Graph illustrates results of receiver operating characteristic analysis of the postcontrast peripheral vessel numbers in 86 breast masses, for classification of benign and malignant disease. The area under the curve is 0.77, and the optimal cutoff value is four postcontrast peripheral vessels. (b) Graph illustrates results of receiver operating characteristic analysis of the combined score for increase in peripheral vessel number and duration of enhancement in 32 axillary lymph nodes, for classification of benign and malignant disease. The area under the curve is 0.86, and the optimal score is 0.41.
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Copyright © 2001 by the Radiological Society of North America.
