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DOI: 10.1148/radiol.2232010742
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(Radiology 2002;223:319-325.)
© RSNA, 2002

Gadolinium Chelates in Angiography and Interventional Radiology: A Useful Alternative to Iodinated Contrast Media for Angiography1

David J. Spinosa, MD, John A. Kaufmann, MD and Gary D. Hartwell, DSc

1 From the Department of Radiology, University of Virginia Health System, 1215 Lee St, Charlottesville, VA 22908 (D.J.S., G.D.H.), and Department of Radiology, Dotter Interventional Institute, Oregon Health Sciences University, Portland (J.A.K.). Received April 6, 2001; revision requested May 18; revision received June 28; accepted July 16. Address correspondence to D.J.S. (e-mail: djs4m@virginia.edu).



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  		Figure 1a. (a, b) From left to right, phantoms demonstrate contrast with 300 mg iodine per milliliter, 150 mg iodine per milliliter, 75 mg iodine per milliliter, 0.5 mmol gadolinium per milliliter (full-strength gadolinium chelate) (arrow), 37.5 mg iodine per milliliter, and 18.75 mg iodine per milliliter. (a) Phantom with 0 cm of water attenuation at 96 kVp. (b) Phantom with 20 cm of water attenuation at 96 kVp. The full-strength gadolinium chelate (arrow) demonstrates image contrast in a range between the contrast levels at 75 and 150 mg iodine per milliliter.

 


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  		Figure 1b. (a, b) From left to right, phantoms demonstrate contrast with 300 mg iodine per milliliter, 150 mg iodine per milliliter, 75 mg iodine per milliliter, 0.5 mmol gadolinium per milliliter (full-strength gadolinium chelate) (arrow), 37.5 mg iodine per milliliter, and 18.75 mg iodine per milliliter. (a) Phantom with 0 cm of water attenuation at 96 kVp. (b) Phantom with 20 cm of water attenuation at 96 kVp. The full-strength gadolinium chelate (arrow) demonstrates image contrast in a range between the contrast levels at 75 and 150 mg iodine per milliliter.

 


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  		Figure 2a. (a) CO2-enhanced abdominal aortogram (left anterior oblique projection) demonstrates right renal artery stenosis (straight arrow). Overlying bowel gas (curved arrow) deteriorates the CO2-enhanced image. (b) Selective gadolinium-enhanced right renal artery angiogram (left anterior oblique projection) obtained with 6 mL of full-strength gadodiamide clearly defines the right renal artery stenosis (arrow). (c) Gadolinium-enhanced angiogram (left anterior oblique projection) obtained after injection of 6 mL of gadodiamide through a vascular sheath (curved arrow) in the abdominal aorta demonstrates a widely patent right main renal artery (straight arrow) after balloon angioplasty and stent placement. POST = postangioplasty.

 


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  		Figure 2b. (a) CO2-enhanced abdominal aortogram (left anterior oblique projection) demonstrates right renal artery stenosis (straight arrow). Overlying bowel gas (curved arrow) deteriorates the CO2-enhanced image. (b) Selective gadolinium-enhanced right renal artery angiogram (left anterior oblique projection) obtained with 6 mL of full-strength gadodiamide clearly defines the right renal artery stenosis (arrow). (c) Gadolinium-enhanced angiogram (left anterior oblique projection) obtained after injection of 6 mL of gadodiamide through a vascular sheath (curved arrow) in the abdominal aorta demonstrates a widely patent right main renal artery (straight arrow) after balloon angioplasty and stent placement. POST = postangioplasty.

 


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  		Figure 2c. (a) CO2-enhanced abdominal aortogram (left anterior oblique projection) demonstrates right renal artery stenosis (straight arrow). Overlying bowel gas (curved arrow) deteriorates the CO2-enhanced image. (b) Selective gadolinium-enhanced right renal artery angiogram (left anterior oblique projection) obtained with 6 mL of full-strength gadodiamide clearly defines the right renal artery stenosis (arrow). (c) Gadolinium-enhanced angiogram (left anterior oblique projection) obtained after injection of 6 mL of gadodiamide through a vascular sheath (curved arrow) in the abdominal aorta demonstrates a widely patent right main renal artery (straight arrow) after balloon angioplasty and stent placement. POST = postangioplasty.

 




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