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DOI: 10.1148/radiol.2232010482
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(Radiology 2002;223:554-557.)
© RSNA, 2002

Measurement of Breast Density with Dual X-ray Absorptiometry: Feasibility1

John A. Shepherd, PhD, Karla M. Kerlikowske, MD, Rebecca Smith-Bindman, MD, Harry K. Genant, MD and Steve R. Cummings, MD

1 From the Department of Radiology, Osteoporosis and Arthritis Research Group (J.A.S., H.K.G.) and Department of Medicine and Epidemiology and Biostatistics (K.M.K., S.R.C.), University of California at San Francisco, 350 Parnassus Ave, Suite 607, San Francisco, CA 94143; Veterans Affairs Medical Center, San Francisco, Calif (K.M.K.); and Department of Radiology, UCSF/Mt Zion Medical Center, San Francisco, Calif (R.S.B.). From the 2000 RSNA scientific assembly. Received February 19, 2001; revision requested March 28; final revision received November 28; accepted December 10. Supported by Breast Cancer Research Program Concept Award DAMD17-00-1-0612 from the Department of Defense and by UCSF Academic Senate Committee on Research. Address correspondence to J.A.S. (e-mail: john.shepherd@oarg.ucsf.edu).



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  		Figure 1. Density-step phantom used to calibrate the DXA device to units of percentage of glandular density. Phantom has a six-step range in percentage of glandular density from 0% (pure adipose fat) to 100% (pure breast glandular tissue).

 


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  		Figure 2. Plot shows results of calculation of 1 minus the percentage of fat measured with the DXA device and the percentage of glandular density reported with the phantom. Error bars are shown but do not extend beyond the dimension of the plot symbol.

 




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