HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kakeda, S. Articles by Doi, K. Search for Related Content PubMed PubMed Citation Articles by Kakeda, S. Articles by Doi, K.

Improved Detection of Lung Nodules by Using a Temporal Subtraction Technique¹

¹ From the Department of Radiology, University of Occupational and Environmental Health School of Medicine, Iseigaoka 1-1, Yahatanisi-ku, Kitakyushu-shi 807-8555, Japan (S. Kakeda, K.N., K.K., H.W., H.N.); Research Center, Nippon Bunri University, Ooita-shi, Japan (S. Katsuragawa); and Kurt Rossmann Laboratories for Radiologic Image Research, Department of Radiology, University of Chicago, Ill (K.D.). Received August 17, 2001; revision requested May 10; final revision received January 8, 2002; accepted January 29. Address correspondence to S. Kakeda (e-mail: kakeda@med.uoeh-u.ac.jp).

View larger version (28K): [in a new window]   Figure 1. Graph shows subjective evaluation of the effect of temporal subtraction images on ease of nodule detection according to nodule subtlety. Black bar = extremely subtle, gray bar = very subtle, bar with narrow diagonal stripes = subtle, bar with wide diagonal stripes = relatively obvious, and white bar = obvious.

View larger version (168K): [in a new window]   Figure 2a. Images show lung cancer in a 68-year-old woman. (a) Previous posteroanterior radiograph, (b) current posteroanterior radiograph, and (c) temporal subtraction image; this last image enhanced the visibility of a nodule (arrows) overlapping the diaphragm.

View larger version (167K): [in a new window]   Figure 2b. Images show lung cancer in a 68-year-old woman. (a) Previous posteroanterior radiograph, (b) current posteroanterior radiograph, and (c) temporal subtraction image; this last image enhanced the visibility of a nodule (arrows) overlapping the diaphragm.

View larger version (169K): [in a new window]   Figure 2c. Images show lung cancer in a 68-year-old woman. (a) Previous posteroanterior radiograph, (b) current posteroanterior radiograph, and (c) temporal subtraction image; this last image enhanced the visibility of a nodule (arrows) overlapping the diaphragm.

View larger version (34K): [in a new window]   Figure 3. Graph shows ROC curves for detecting lung nodules with and without use of temporal subtraction images.

View larger version (29K): [in a new window]   Figure 4. Graph shows the number of cases (>20%) affected by temporal subtraction images in confidence rating with regard to nodular cases (A-H represent the eight readers).

View larger version (25K): [in a new window]   Figure 5. Graph shows the number of cases (>20%) affected by temporal subtraction images in confidence rating with regard to nonnodular cases (A-H represent the eight readers).

View larger version (49K): [in a new window]   Figure 6. Graph shows the average number of cases (>20%) affected by temporal subtraction images according to subtlety in nodular cases.

View larger version (173K): [in a new window]   Figure 7a. Images show organizing pneumonia in a 77-year-old man. (a) Previous posteroanterior radiograph, (b) current posteroanterior radiograph, and (c) temporal subtraction image; this last image enhanced the visibility of a subtle nodule (arrow) that was difficult to recognize on conventional radiographs alone.

View larger version (174K): [in a new window]   Figure 7b. Images show organizing pneumonia in a 77-year-old man. (a) Previous posteroanterior radiograph, (b) current posteroanterior radiograph, and (c) temporal subtraction image; this last image enhanced the visibility of a subtle nodule (arrow) that was difficult to recognize on conventional radiographs alone.

View larger version (191K): [in a new window]   Figure 7c. Images show organizing pneumonia in a 77-year-old man. (a) Previous posteroanterior radiograph, (b) current posteroanterior radiograph, and (c) temporal subtraction image; this last image enhanced the visibility of a subtle nodule (arrow) that was difficult to recognize on conventional radiographs alone.