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Published online before print June 28, 2002, 10.1148/radiol.2242011322
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Hepatic Metastases in Patients with Colorectal Cancer: Relationship between Size of Metastases, Standard of Reference, and Detection Rates1

Arian R. van Erkel, MD, Milan E. J. Pijl, MD, Annette A. van den Berg-Huysmans, MSc, Martin N. J. M. Wasser, MD, Cornelis J. H. van de Velde, MD and Johan L. Bloem, MD

1 From the Departments of Radiology (A.R.v.E., M.E.J.P., A.A.v.d.B.H., M.N.J.M.W., J.L.B.) and Oncological Surgery (C.J.H.v.d.V.), Leiden University Medical Center, Albinusdreef 2, PO Box 9600, 2300 RC Leiden, the Netherlands. Received August 3, 2001; revision requested September 10; revision received November 14; accepted January 7, 2002. M.E.J.P. supported by the Dutch Cancer Foundation, with a grant for work on the detection of hepatic metastases in patients with colorectal cancer. Address correspondence to A.R.v.E. (e-mail: a.r.van_erkel@lumc.nl).



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  		Figure 1. Histogram shows size distribution of 355 focal hepatic lesions in 47 patients with colorectal cancer who underwent surgery for resection of metastases or for isolated hepatic perfusion.

 


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  		Figure 2. Graph shows correlation between the highest reported detection rate and the fraction of metastases smaller than 10 mm. In three studies (solid markers), intraoperative US was used in only part of the population. In the other four studies (open markers), intraoperative US was used in all patients. A higher fraction of small metastases was associated with a lower detection rate (two-tailed Pearson correlation test, -0.988; P = .012).

 




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