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DOI: 10.1148/radiol.2251011744
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Malignant Biliary Obstruction: Treatment with ePTFE-FEP– covered Endoprostheses—Initial Technical and Clinical Experiences in a Multicenter Trial1

Maria Schoder, MD, Plinio Rossi, MD, Renon Uflacker, MD, Mario Bezzi, MD, Alfred Stadler, MD, MSc, Martin A. Funovics, MD, Manfred Cejna, MD and Johannes Lammer, MD

1 From the Department of Angiography and Interventional Radiology, University of Vienna Medical School, Waehringerguertel 18-20, A-1090 Vienna, Austria (M.S., A.S., M.A.F., M.C., J.L.); Department of Radiology, University of Rome "La Sapienza," Italy (P.R., M.B.); and Interventional Radiology, Medical University of South Carolina, Charleston (R.U.). Received October 25, 2001; revision requested December 3; revision received February 15, 2002; accepted March 14. Address correspondence to M.S. (e-mail: maria.schoder@univie.ac.at).



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Figure 1. Biliary endoprosthesis used in current study. Stent structure consists of a helically wound nitinol wire with anchoring fins at each end that are bound to the outer surface of the ePTFE-FEP tubular lining.

 


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Figure 2a. Percutaneous transhepatic cholangiograms obtained in an 83-year-old woman with pancreatic cancer obstructing the common bile duct. (a) Cholangiogram shows the common bile duct has irregular margins and a short obstruction (arrow). (b) Cholangiogram shows the delivery system placed with the distal end at the level of the papilla (arrow). (c) Cholangiogram obtained after deployment and dilation of the stent shows a fully expanded endoprosthesis. Arrows point to the upper and lower ends of the endoprosthesis.

 


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Figure 2b. Percutaneous transhepatic cholangiograms obtained in an 83-year-old woman with pancreatic cancer obstructing the common bile duct. (a) Cholangiogram shows the common bile duct has irregular margins and a short obstruction (arrow). (b) Cholangiogram shows the delivery system placed with the distal end at the level of the papilla (arrow). (c) Cholangiogram obtained after deployment and dilation of the stent shows a fully expanded endoprosthesis. Arrows point to the upper and lower ends of the endoprosthesis.

 


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Figure 2c. Percutaneous transhepatic cholangiograms obtained in an 83-year-old woman with pancreatic cancer obstructing the common bile duct. (a) Cholangiogram shows the common bile duct has irregular margins and a short obstruction (arrow). (b) Cholangiogram shows the delivery system placed with the distal end at the level of the papilla (arrow). (c) Cholangiogram obtained after deployment and dilation of the stent shows a fully expanded endoprosthesis. Arrows point to the upper and lower ends of the endoprosthesis.

 


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Figure 3. Graph shows cumulative results of Kaplan-Meier analysis of survival after implantation of biliary endoprostheses. Crosses indicate censored events, and x axis indicates days after implantation of endoprosthesis.

 


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Figure 4. Graph shows cumulative results of Kaplan-Meier analysis of primary patency over time after implantation of biliary endoprostheses. Crosses indicate censored events, and x axis indicates days after implantation of endoprosthesis.

 


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Figure 5. Graph shows cumulative results of Kaplan-Meier analysis of time (in days) to composite end point (ie, recurrent stent obstruction or death with patent stent) after implantation of biliary endoprosthesis. Crosses indicate censored events, and x axis indicates days after implantation of endoprosthesis.

 





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